The Activin Receptor Type IIA (RIIA) Antibody from MyBioSource.com is a Goat Polyclonal antibody to ACVR2A. This antibody recognizes Human antigen. The Activin Receptor Type IIA (RIIA) Antibody has been shown to work in the following applications: EIA, Immunoassay, Block/Neutralize/Inhibit, ELISA, Immunohistochemistry, and Western Blot.
Description
Members of the TGF-beta superfamily exert their biological effects by binding to heteromeric complexes of a type I and a type II serine-threonine kinase receptor, both of which are essential for signal transduction. Activin receptor type IIB is a type II receptor that mediates multiple signals for transforming growth factor-beta (TGF-beta) family members, including Activin, Nodal, Bmp7, Gdf1, Gdf3, Myostatin (Gdf8), and Gdf11. Through alternative mRNA splicing, multiple ActR-IIB isoforms can also be generated