The Integrin, alpha9 (Integrin alpha4-like) Antibody from MyBioSource.com is a Goat Polyclonal antibody to ITGA9. This antibody recognizes Human, and Mouse antigen. The Integrin, alpha9 (Integrin alpha4-like) Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, and Western Blot.
Description
Integrin alpha9 is a 150kD type I transmembrane glycoprotein that is widely expressed and is found on smooth muscle, keratinocytes, skeletal muscle and hepatocytes. It principally associates with the beta1 integrin. Alpha9beta1 binds to VEGF-C and D, and osteopontin. The 951 amino acid (aa) extracellular domain of mouse integrin alpha9 contains three beta-propellor repeats and multiple PheGly-GlyAlaPro repeats. A potential proteolytic cleavage site in human alpha9 ECD is absolutely conserved in mouse alpha9 ECD (Arg 566-Val 567). The ECD of mouse integrin alpha9 shares 95% and 89% aa sequence identity to rat and human integrin alpha9, respectively