The RAD51L1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to REC2. This antibody recognizes Human antigen. The RAD51L1 Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata