The IPO8 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Importin 8, IPO8, and Om1. This antibody recognizes Human, Mouse, and Rat antigen. The IPO8 Polyclonal Antibody has been shown to work in the following applications: ELISA, and Immunohistochemistry.
Description
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene