Rabbit anti-Phospho RPA32 (S33) Antibody, Affinity Purified from Bethyl Laboratories, Inc.

Yes, the Rabbit anti-Phospho RPA32 (S33) Antibody has been utilized in research examining the role of RPA32 in viral DNA replication, specifically in the context of Human Parvovirus B19. The antibody was shown to be essential for the viral DNA replication process, as RPA32 is recruited to the centers of viral DNA replication, although its phosphorylation was not necessary for this function (zou2018).

The Rabbit anti-Phospho RPA32 (S33) Antibody has been successfully used in immunofluorescence assays, as indicated in a study where it was employed alongside other antibodies to analyze cellular responses to DNA damage and replication stress (hawks2023).

This antibody specifically targets the phosphorylated serine at position 33 of RPA32. Phosphorylation at this site is significant as it is involved in the cellular response to DNA damage and replication stress, which are critical for maintaining genome stability during DNA replication.

The Rabbit anti-Phospho RPA32 (S33) Antibody is reactive with human proteins, making it suitable for studies involving human cell lines and tissues, particularly in the context of DNA damage response and replication stress in human cells.