The APPL1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to APPL, and appl1. This antibody recognizes Human, Mouse, and Rat antigen. The APPL1 Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus