MyBioSource.com's Rabbit Polyclonal to Human Nor-1 / NR4A3 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed. The Rabbit Polyclonal to Human Nor-1 / NR4A3 Antibody was generated using NR4A3 as the antigen and it reacts with Human, Bovine, Canine, Non-Human Primate, Porcine, and Rabbit.
Description
NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats