The Rabbit Anti-TNFRSF10B / Killer / DR5 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TNFRSF10B. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-TNFRSF10B / Killer / DR5 Antibody has been shown to work in the following applications: Immunocytochemistry, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently