The Goat Anti-CFH / Complement Factor H Antibody from MyBioSource.com is a Goat Polyclonal antibody to CFH, and complement factor H. This antibody recognizes Human, and Non-Human Primate antigen. The Goat Anti-CFH / Complement Factor H Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Factor H (CFH) is a protein with twenty short consensus repeat (SCR) domains. Factor H is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in Factor H have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized