MyBioSource.com's Rabbit Anti-GABABR1 / GABBR1 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed. The Rabbit Anti-GABABR1 / GABBR1 Antibody was generated using GABBR1 as the antigen and it reacts with Human, Mouse, Rat, Bovine, Hamster, Non-Human Primate, Porcine, and Rabbit.
Description
GABA(B) receptor 1, a GABA(B) Receptor, forms a heterodimer with GABA(B) receptor 2 to mediate the effects of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in the central nervous system. Activation of this receptor leads to fast synaptic inhibition. Reduced GABA(B) receptor 1a-b expression is implicated in the pathophysiology of temporal-lobe epilepsy