The RAT ANTI MOUSE Ly-6A/E Antibody from MyBioSource.com is a Rat Monoclonal antibody to Ly6a, and lymphocyte antigen 6 complex, locus A. This antibody recognizes Mouse antigen. The RAT ANTI MOUSE Ly-6A/E Antibody has been shown to work in the following applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Rat anti Mouse Ly-6A/E antibody, clone D7 recognises members of the lymphocyte activation protein-6 (Ly-6) multigene family. Specifically, it recognises Ly-6A.2 and Ly-6E.1. Ly-6A/E is also known as stem cell antigen-1 (Sca-1). It is an 18kDa mouse glycosyl phosphatidylinositol-anchored cell surface protein of the Ly-6 gene family. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly-6.1 and Ly-6.2 allotypes. As such, it is the most common marker used for enriching adult hematopoietic stem cells. It has varied functions, it plays a role in bone formation, myoblast proliferation and differentiation and the activation and immunosuppressive function of T cells. Rat anti Mouse Ly-6A/E antibody, clone D7 has been reported to induce T cell activation. Removal of Sodium Azide is recommended prior to use in functional assays. MyBioSource recommend the use of EQU003 for this purpose