The Goat Polyclonal to Human IDS Antibody from MyBioSource.com is a Goat Polyclonal antibody to IDS, and Iduronate 2-sulfatase. This antibody recognizes Human, and Non-Human Primate antigen. The Goat Polyclonal to Human IDS Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. A splice variant of this gene has been described