MyBioSource.com's C2CD3 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The C2CD3 Antibody was generated using C2CD3, and Miscellaneous as the antigen and it reacts with Human, Mouse, and Rat.
Description
C2CD3, a putative calcium-dependent lipid-binding protein, is an essential regulator of intracellular transduction of the Hedgehog signal (1). It is localized at the basal body of cilia, mediates calcium-dependent vesicular transport and/or recruitment of proteins and regulates cilium biogenesis by promoting the assembly of centriolar distal appendages critical for docking ciliary vesicles and recruiting other essential ciliogenic proteins (2,3). C2CD3 directly promotes centriole elongation and OFD1 acts as a negative regulator of C2CD3 (4,5)