RABBIT ANTI HUMAN RFI MBS222824 from MyBioSource.com

Description

MBS222824 detects human Ring Finger homologous to Inhibitor of apoptosis protein (hRFI), an anti-apoptotic protein which has been shown to be a novel modulator of NF-kB activation, leading to the upregulation of Bcl2 and BclXL. It is also thought to possess E3 ubiquitin protein ligase activity and has been shown to target caspases 8 and 10 for proteasomal degradation. hRFI is expressed ubiquitously, and has been localized to both the nucleus and the cytoplasm. hRFI is also expressed in oesophageal, gastric and colorectal cancers, suggesting a possible association between hRFI and the development of digestive tract cancers

Product Specs
ItemRABBIT ANTI HUMAN RFI
CompanyMyBioSource.com
Price $390.00Supplier Page View Company Product Page
Catalog NumberMBS222824
Quantity0.1 mg
ApplicationsELISA (EIA), Western Blot (WB)
ConcentrationIgG concentration 1.0mg/ml
Conjugate/TagUnconjugated
FormatPurified
Purified IgG - liquid
ReactivityBovine (Expected from Sequence), Dog (Expected from Sequence), Mouse (Expected from Sequence), New World primate (Expected from Sequence), Rat (Expected from Sequence)
TargetRFI
IsotypeIgG
Molecular Weight41,797 Da
HostRabbit
ImmunogenThis item detects human Ring Finger homologous to Inhibitor of apoptosis protein (hRFI), an anti-apoptotic protein which has been shown to be a novel modulator of NF-kB activation, leading to the upregulation of Bcl2 and BclXL. It is also thought to possess E3 ubiquitin protein ligase activity and has been shown to target caspases 8 and 10 for proteasomal degradation.

hRFI is expressed ubiquitously, and has been localized to both the nucleus and the cytoplasm. hRFI is also expressed in oesophageal, gastric and colorectal cancers, suggesting a possible association between hRFI and the development of digestive tract cancers
NCBI Full Gene Namering finger protein 34, E3 ubiquitin protein ligase
NCBI Gene AliasesCARP-1, hRFI, RIFF, RIF, RFI, CARP1
ClonalityPolyclonal