MyBioSource.com's Rabbit Anti-EDNRA / Endothelin A Receptor Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed. The Rabbit Anti-EDNRA / Endothelin A Receptor Antibody was generated using EDNRA as the antigen and it reacts with Human, and Non-Human Primate.
Description
The ETA receptor is an Endothelin Receptor that mediates the effects of endothelin-1, a mitogen with potent contractile properties. In the human fetal olfactory epithelium cell line FNC-B4, the ETA receptor increases the secretion of gonadotropin-releasing hormone. Increased ETA concentration may be correlated with smooth muscle hypertrophy observed in patients suffering from bladder-outlet obstruction