The Goat Polyclonal to Human NOVA1 Antibody from MyBioSource.com is a Goat Polyclonal antibody to NOVA1. This antibody recognizes Human, Mouse, Rat, Bovine, Canine, Chicken/Bird, Non-Human Primate, Porcine, Rabbit, Xenopus/Amphibian, and Other Mammalian antigen. The Goat Polyclonal to Human NOVA1 Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Neuron-specific RNA-binding protein that is inhibited by paraneoplastic antibodies. NOVA1 is recognized by sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced forms are present in brain and tumor cells. These transcript variants differ by the inclusion of 72bp exon H as well as a 9bp motif. NOVA1 is a member of the Nova family of paraneoplasic disease antigens