MyBioSource.com's Rabbit Polyclonal to Human CDK12 / CRKRS Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed. The Rabbit Polyclonal to Human CDK12 / CRKRS Antibody was generated using CDK12 as the antigen and it reacts with Human, Canine, and Non-Human Primate.
Description
CRK7 is a CDC2/CDK -type protein kinase. Also known as CRKRS, the protein has an arginine/serine-rich (RS) domain that is found predominantly in splicing factors, and extensive proline-rich regions that match the consensus for SH3 and WW domain binding sites. Anti-CrkRS immunoprecipitates have been shown to phosphorylate the C-terminal domain of RNA polymerase II in vitro