The GRIK2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to EAA2, GluK2, GluK5, GluR6, Glutamate Receptor, GRIK2, and GRIK5. This antibody recognizes Human, Mouse, and Rat antigen. The GRIK2 Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation