Erk5 (D23E9) Rabbit mAb 3552S from Cell Signaling Technology

Product Specs
ItemErk5 (D23E9) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number3552S
Quantity100 µl
ApplicationsW
ReactivityH, M, R, Mk
TargetERK5
HostRabbit
NCBI Gene AliasesBMK1, ERK4, ERK5, PRKM7
ClonalityMonoclonal
NCBI Full Gene Namemitogen-activated protein kinase 7
Research AreaMAP Kinase Signaling
IsotypeIgG
CloneD23E9
Molecular Weight115

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Dissecting Context-Specific Effects of ERK5 Signaling in Triple-Negative Breast CancerCancers (Basel)January 26, 2026Katherine L. Hebert, Sarah B. Knopf, Thomas Cheng, Megan C. Benz, Bridgette M. Collins-Burow, Jorge A. Belgodere, Frank H. Lau, Elizabeth C. Martin, Matthew E. Burow, Van H. BarnesCell Signaling Technology, Catalog Number 4814T; and ERK5: Cell Signaling Technology, Catalog Number 3552S). After three 5 min washes in 1% Tris-Buffered Saline with Tween 20 (TBS-T), membranes were incubated

(2) Optimization of an Hsp90β-selective inhibitor via exploration of the Hsp90 N-terminal ATP-binding pocketEuropean Journal of Medicinal ChemistryNovember 5, 2025Michael A. Serwetnyk, Taddäus Strunden, Ian Mersich, Deborah Barlow, Terin D'Amico, Sanket J. Mishra, Karen L. Houseknecht, John M. Streicher, Brian S. J. Blagg7% nonfat dry milk solution and probed with antibodies against GAPDH, Hsp90, Hsp70, (Cell Signaling, 3552), Cdk4 (Cell Signaling, 12790), and Akt (Cell Signaling, 9272). Antibody dilutions were 1:1000 and secondary

(3) SMYD5 methylation of rpL40 links ribosomal output to gastric cancerNatureAugust 15, 2024Juhyung Park, Jibo Wu, Krzysztof J. Szkop, Jinho Jeong, Predrag Jovanovic, Dylan Husmann, Natasha M. Flores, Joel W. Francis, Ying-Jiun C. Chen, Ana Morales Benitez, et al.13901), ATF6 (Proteintech, 24169-1-AP), CCND1 (CST, 2978), CDK4 (Proteintech, 11026-1-AP), MAPK7 (CST, 3552), SOX9 (Proteintech, 67439-1-Ig), SRF (CST, 5147), CD45 (CST, 70257), MYC (CST, 5605), anti-mouse and

(4) TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal developmentiScienceAugust 18, 2023Erdyni N. Tsitsikov, Khanh P. Phan, Yufeng Liu, Alla V. Tsytsykova, Mike Kinter, Lauren Selland, Lori Garman, Courtney Griffin, Ian F. Dunn1706404); and probed with antibodies from CellSignaling: MEKK3 (5727), MEKK2 (5727), MARK2 (9118), ERK5 (3552), MEK5 (40737), and SCRIB (4475). Sp1 antibody (Sigma Aldrich, 07-645), and α-tubulin (3873) were used

(5) Hepatitis B Virus X Protein Modulates p90 Ribosomal S6 Kinase 2 by ERK to Promote Growth of Hepatoma CellsVirusesMay 17, 2023Ning Han, Qingbo Zhang, Xiaoqiong Tang, Lang Bai, Libo Yan, Hong Tang(Cell Signaling Technology, Danvers, MA, USA, 1:1000, 9197), Erk (Cell Signaling Technology, Danvers, MA, USA, 1:1000, 3552), p-Erk (Cell Signaling Technology, Danvers, MA, USA, 1:1000, 4370), p38 (Cell Signaling Technology,

(6) Proteogenomics of diffuse gliomas reveal molecular subtypes associated with specific therapeutic targets and immune-evasion mechanismsNature communicationsJanuary 31, 2023Wang Y, Luo R, Zhang X, Xiang H, Yang B, Feng J, Deng M, Ran P, Sujie A, Zhang F, et al.primary antibodies (anti-β-actin (dilution 1:1000), anti-Flag (dilution 1:5000), anti-ERK5(CST, cat#3552, dilution 1:1000), anti-PRPS1 (dilution 1:1000), anti-PRPS2 (dilution 1:1000), anti-PPAT (dilution 1:1000),

(7) TIMP-2 regulates 5-Fu resistance via the ERK/MAPK signaling pathway in colorectal cancerAging (Albany NY)January 15, 2022Guolin Zhang et al.Antibodies to MAPK (Erk1/2) (Cat No.4695), phospho-MAPK (Erk1/2) (Thr202/Tyr204) (Cat No.4370), Erk5 (Cat No.3552), phospho-Erk5 (Thr218/Tyr220) (Cat No.3371) and GAPDH (Cat No. 97166) were purchased from Cell Signaling Technology

(8) The Development of Hsp90β-Selective Inhibitors to Overcome Detriments Associated with pan-Hsp90 InhibitionJournal of Medicinal ChemistryFebruary 11, 2021Sanket J. Mishra et al.7% non-fat dry milk solution. Blots were probed with antibodies raised against Erk5 (Cell Signaling, 3552S), CDK4, (Cell Signaling, 12790S), CDK6 (Cell Signaling, 3136S), beta-Actin (Cell Signaling, 3700S),

(9) Gal-1 (Galectin-1) Upregulation Contributes to Abdominal Aortic Aneurysm Progression by Enhancing Vascular InflammationArteriosclerosis, thrombosis, and vascular biologyJanuary 1, 2021Chiang MT, Chen IM, Hsu FF, Chen YH, Tsai MS, Hsu YW, Leu HB, Huang PH, Chen JW, Liu FT, et al.signal-regulated kinase; 9102S; Cell Signaling), anti-phospho-Erk1/2 (9101S; Cell Signaling), antiErk5 (3552S; Cell Signaling), anti-phospho-Erk5 (sc-135760; Santa Cruz), anti-JNK (c-jun N-terminal kinase; 9252S;

(10) Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesisNature communicationsOctober 26, 2020Hultgren NW, Fang JS, Ziegler ME, Ramirez RN, Phan DTT, Hatch MMS, Welch-Reardon KM, Paniagua AE, Kim LS, Shon NN, et al.Abcam 22614), rabbit anti-pERK5 (1:1000, Cell Signaling 3371), rabbit anti-ERK5 (1:1000, Cell Signaling 3552), rabbit anti-alpha-Tubulin (1:2000, Cell Signaling 2144), rabbit anti-GAPDH (1:2000, Cell Signaling

(11) ERK5 Is Required for Tumor Growth and Maintenance Through Regulation of the Extracellular Matrix in Triple Negative Breast CancerFrontiers in OncologyAugust 3, 2020Van T. Hoang et al.(CDH1: Cell Signaling Technology, Catalog Number 3195; ERK5: Cell Signaling Technology, Catalog Number 3552; p-ERK5: Santa Cruz, Catalog Number 135761). After three 15-min washes in 1% TBS-T, membranes were incubated

(12) Effect of naive and cancer-educated fibroblasts on colon cancer cell circadian growth rhythmCell death & diseaseApril 27, 2020Parascandolo A, Bonavita R, Astaburuaga R, Sciuto A, Reggio S, Barra E, Corcione F, Salvatore M, Mazzoccoli G, Relógio A, et al.α-CREB (Upstate, 06-863), α-pERK5 (Merck KGaA, 07-507, Darmstadt, Germania), α-ERK5 (Cell Signaling, 3552S), and α-tubulin (Cell Signaling). ProtoArray analysis To analyse differences in cytokine and soluble

(13) The MEK5–ERK5 Kinase Axis Controls Lipid Metabolism in Small-Cell Lung CancerCancer ResearchMarch 15, 2020Sandra Cristea et al.antibodies and dilutions used were as follows: ERK5 (D23E9) rabbit mAb (Cell Signaling Technology, CST #3552, 1:100), ERK5 (D3I5V) rabbit mAb (CST, #12950, 1:50) phospho-ERK5 (Thr218/Tyr220) rabbit polyclonal

(14) Tracing fluid saturation during pegmatite differentiation by studying the fluid inclusion evolution and multiphase cassiterite mineralisation of the Gatumba pegmatite dyke system (NW Rwanda)LithosFebruary 1, 2020Niels Hulsbosch, Philippe Muchez66848 8727 50 1702-3-I2-D-4 40 986 75765 <6 51 1702-3-I2-D-5 30 1248 81177 2798 52 1702-3-I2-D-6 30 3552 62964 526 53 1702-3-I2-D-7 30 2419 68011 351 55 1037-2-Cst-2 40 1329 68968 2381 56 1037-2-Cst-3 40 1108

(15) Enhanced JunD/RSK3 signalling due to loss of BRD4/FOXD3/miR-548d-3p axis determines BET inhibition resistanceNature communicationsJanuary 14, 2020Tai F, Gong K, Song K, He Y, Shi J.phospho-MEK1/2 (#9154), MEK1/2 (#8727), phospho-ERK1/2 (#4370), ERK1/2 (#4695), phospho-ERK5 (#3371), ERK5 (#3552), c-Fos (#2250), c-Jun (#9165) and caspase-3 (#14220) were purchased from Cell Signalling (Danvers,

(16) Sex-specific lung functional changes in adult mice exposed only to second-hand smoke in uteroRespiratory researchJune 27, 2017Noël A, Xiao R, Perveen Z, Zaman H, Le Donne V, Penn A.the TransBlot Turbo™ Transfer System (Bio-Rad). Antibodies to Page 4 of 12 ERK5 or MAPK7 (Cat. No. 3552) and β-actin (ACTB, Cat. No. 4967 L), as the control, were purchased from Cell Signaling Technology

(17) L-selectin mechanochemistry restricts neutrophil priming in vivoNature communicationsMay 12, 2017Liu Z, Yago T, Zhang N, Panicker SR, Wang Y, Yao L, Mehta-D'souza P, Xia L, Zhu C, McEver RP.

(18) The p70S6K Specific Inhibitor PF-4708671 Impedes Non-Small Cell Lung Cancer GrowthPLOS ONEJanuary 15, 2016Zhi-Xin Qiu, Rong-Fei Sun, Xian-Ming Mo, Wei-Min Li#BS3610, 1;1000, Bioworld Technology, Nanjing, China), anti-BAD, anti-Caspase3, anti-ERK (#9239P, #96625, #3552S, 1:1000, Cell Signaling Technology), and anti-β-actin (#4970, 1:5000, Cell Signaling Technology) antibodies,

(19) Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinomaBMC CancerDecember 1, 2015Paul R. Gavine et al.Amersham ECL detection reagents (GE health). The primary antibodies included: MAPK7 antibody (CST, #3552), pMAPK7 (T218/Y220) (CST, #3371), pMEF2A (T312) (Abcam, ab#30644), MEF2A (Abcam, ab#32866), and HA

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Erk5 (D23E9) Rabbit mAb

Erk5 (D23E9) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Erk5 (D23E9) Rabbit mAb from Cell Signaling Technology

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