Bioss Inc.'s LXR alpha + LXR beta Antibody, Biotin Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot. The LXR alpha + LXR beta Antibody, Biotin Conjugated was generated using NR1H2, and NR1H3 as the antigen and it reacts with Homo Sapiens, Human, and Rat.
Description
The LXR receptors (including LXR-_ and LXR-_) bind oxysterols and play key roles in maintaining cholesterol homeostasis in macrophages, primarily by regulating multiple components of the reverse cholesterol transport. They also are potent inhibitors of inflammation and are capable of repressing cytokine and chemokine production by Toll-like receptor (TLR)-activated macrophages