The LXR alpha + LXR beta Antibody, HRP Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to NR1H2, and NR1H3. This antibody recognizes Homo Sapiens, Human, and Rat antigen. The LXR alpha + LXR beta Antibody, HRP Conjugated has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
The LXR receptors (including LXR-_ and LXR-_) bind oxysterols and play key roles in maintaining cholesterol homeostasis in macrophages, primarily by regulating multiple components of the reverse cholesterol transport. They also are potent inhibitors of inflammation and are capable of repressing cytokine and chemokine production by Toll-like receptor (TLR)-activated macrophages