LIN28B Antibody 4196S from Cell Signaling Technology

Product Specs
ItemLIN28B Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number4196S
Quantity100 µl
ApplicationsW, IP
ReactivityH
TargetLin28B
HostRabbit
NCBI Gene AliasesCSDD2
NCBI Full Gene Namelin-28 homolog B
ClonalityPolyclonal
Research AreaDevelopmental Biology
Molecular Weight32, 21

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Developmental reprogramming underlies chemotherapy resistance in favorable-histology Wilms tumorCell ReportsMarch 24, 2026Andrew M. Fleming, Carolyn M. Jablonowski, Hongjian Jin, Siwei Zhang, Surbhi Sona, Ha Won Lee, Karissa M. Dieseldorff Jones, Changde Cheng, Beisi Xu, Christopher L. Morton, et al.monoclonal rabbit; 1:1000 dilution; Immunohistochemistry; 1:400 dilution),Cell Signaling Technology,cat#4196S; RRID:AB_2135047 N-MYC ((D1V2A) Western Blot; monoclonal rabbit; 1:1000 dilution),Cell Signaling Technology,cat#84406S;

(2) PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant AscitesAdvanced ScienceMarch 1, 2026Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, et al.5′‐GGAUGUAUUUGUACACCAAtt‐3′;5′‐UUGGUGUACAAAUACAUCCtt‐3′. The following antibodies were used: anti‐human LIN28B (Cell Signaling Technology, 4196S, 1:1000), anti‐mouse Lin28b (Proteintech, 11724‐1‐AP, 1:500), anti‐β‐actin (ABclonal, AC026, 1:10000),

(3) HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticityNat CommunMay 26, 2025Stephanie Dobersch, Naomi Yamamoto, Aidan Schutter, Sarah M. Cavender, Tess M. Robertson, Nithya Kartha, Annie N. Samraj, Ben Doron, Lisa A. Poole, Cynthia L. Wladyka, et al.Proteintech #14642-1-AP), anti-b-actin (1:1000, Sigma Aldrich #A5316), anti-LIN28B (1:1000, Cell Signaling #4196), anti-pS6K T389 (1:1000, Cell Signaling #9234), anti-pS6K T229 (1:1000, R&D Biosystems #MAB8964-SP),

(4) DFMO inhibition of neuroblastoma tumorigenesisCancer MedicineMay 1, 2024Divya Gandra, David H. Mulama, David M. Foureau, Kimberly Q. McKinney, Elizabeth Kim, Kaitlyn Smith, Jason Haw, Abhinav Nagulapally, Giselle L. Saulnier Shollermonoclonal antibody to ODC1 (# ab126590), (Abcam, Cambridge, UK), rabbit monoclonal antibody to LIN28B (#4196), N‐MYC (#9405), and β‐Actin (#4970), (Cell Signaling, Danvers, MA). Goat anti‐rabbit and goat anti‐mouse

(5) A Multi-Omics Approach Reveals Enrichment in Metabolites Involved in the Regulation of the Glutathione Pathway in LIN28B-Dependent Cancer CellsInternational Journal of Molecular SciencesJanuary 27, 2024Matteo Stocchero, Diana Corallo, Silvia Bresolin, Marcella Pantile, Paola Pirillo, Roberta Bortolozzi, Sara Menegazzo, Daniele Boso, Giampietro Viola, Eugenio Baraldi, et al.elsewhere [36]. Primary antibodies used in the study were anti-LIN28B (Cell Signaling, Danvers, CA, USA; 4196S) and anti-Vinculin (Santa Cruz, Dallas, TX, USA; sc-73264). For protein visualization, secondary horseradish-peroxidase

(6) hnRNP Q/SYNCRIP interacts with LIN28B and modulates the LIN28B/let-7 axis in human hepatoma cellsPloS oneJanuary 1, 2024Chang JJ, Lin T, Jhang XY, Chan SP.4693132001). 1 μg antibody against hnRNP Q/SYNCRIP (Atlas Antibodies, HPA041275), LIN28B (Cell Signaling, #4196), or rabbit IgG1 (Sigma, I5006) was conjugated to 50 μl Dynabeads M-280 sheep anti-rabbit IgG (Invitrogen,

(7) The LIN28B-let-7-PBK pathway is essential for group 3 medulloblastoma tumor growth and survivalMolecular oncologySeptember 1, 2023Shahab SW, Roggeveen CM, Sun J, Kunhiraman H, McSwain LF, Juraschka K, Kumar SA, Saulnier O, Taylor MD, Schniederjan M, et al.then were antigen retrieved for 40 min with CC1 reagent (#950‐500, Ventana). Rabbit anti‐LIN28B (CST #4196), anti‐Ki67 (Abcam ab16667, Cambridge, UK), anti‐cleaved caspase‐3 (CST #9661), and anti‐c‐MYC (Abcam

(8) UBE2K regulated by IGF2BP3 promotes cell proliferation and stemness in pancreatic ductal adenocarcinomaInternational journal of oncologyApril 1, 2023Fu W, Lei X, Lu Q, Zhang J, Guo J, Zhao J, Tong X, Hu X.Reagents Co., Ltd.; cat. no. 4903; 1:2,000), anti-LIN28B (CST Biological Reagents Co., Ltd.; cat. no. 4196; 1:1,000), GAPDH (Affinity Biosciences; cat. no. AF7021; 1:6,000), and anti-β-ACTIN (Affinity Biosciences;

(9) Pharmacological inhibition of Lin28 promotes ketogenesis and restores lipid homeostasis in models of non-alcoholic fatty liver diseaseNature communicationsDecember 26, 2022Lekka E, Kokanovic A, Mosole S, Civenni G, Schmidli S, Laski A, Ghidini A, Iyer P, Berk C, Behera A, et al.RPN 2232). Primary antibodies used were: anti-Lin28 (#8706, Cell Signaling; 1:1000), anti-Lin28b (#4196, Cell Signaling; 1:1000), anti-Lin28b (mouse preferred) (#5422, Cell Signaling; 1:1000), anti-insulin

(10) The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myelomaThe EMBO journalOctober 17, 2022Paulmann C, Spallek R, Karpiuk O, Heider M, Schäffer I, Zecha J, Klaeger S, Walzik M, Öllinger R, Engleitner T, et al.#F7425), HA (1:1,000, rabbit, Cell Signaling #3724), LIN28B (1:1,000–1:10,000, rabbit, Cell Signaling #4196), MYC (1:1,000, mouse, clone 9E10, Santa Cruz #sc‐40), OTUD6B (1:1,000, rabbit, Abcam #ab127714), p27

(11) RNA uridyl transferases TUT4/7 differentially regulate miRNA variants depending on the cancer cell typeRNA (New York, N.Y.)March 1, 2022Medhi R, Price J, Furlan G, Gorges B, Sapetschnig A, Miska EA.ZCCHC6 (Merck, Cat. #HPA020620), LIN28A (Cell Signaling, Cat. #3978), LIN28B (Cell Signaling, Cat. #4196), and Tubulin (Merck, Cat. #9026). Secondary antibodies used were anti-rabbit (GE Healthcare, Cat. #NA934)

(12) Bex1 is essential for ciliogenesis and harbours biomolecular condensate-forming capacityBMC biologyFebruary 10, 2022Hibino E, Ichiyama Y, Tsukamura A, Senju Y, Morimune T, Ohji M, Maruo Y, Nishimura M, Mori M.1:100), PCNT (Abcam, ab4448, 1:500), PCNT-Alexa 594 (Novus, NB100-61071AF594, 1:200), LIN28B (CST, #4196S, 1:200), G3BP1 (Bethyl, A302-033A, 1:500) and tubulin (CST, #2148, 1:200) at 4°C overnight. After washing

(13) Fhit induces the reciprocal suppressions between Lin28/Let-7 and miR-17/92miRInternational journal of medical sciencesJanuary 1, 2021Chae HJ, Seo JB, Kim SH, Jeon YJ, Suh SS.(Amersham Pharmacia). Immunoblot analyses were performed using the following antibodies: Lin28B (Cat#4196, Cell Signaling), Lin28A (Cat#3695, Cell Signaling), Fhit (Cat#71-9000, ThermoFisher Scientific), and

(14) Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translationNature geneticsFebruary 1, 2020Basak A, Munschauer M, Lareau CA, Montbleau KE, Ulirsch JC, Hartigan CR, Schenone M, Lian J, Wang Y, Huang Y, et al.(BioRad). Western blots were performed with BCL11A (14B5; ab19487, AbCam, at a 1:100 dilution), LIN28B (4196, Cell Signaling, at a 1:1,000 dilution), β-actin (AC15; Sigma, at a 1:2,500 dilution), β-tubulin (ab6046,

(15) Transposable elements drive widespread expression of oncogenes in human cancersNature GeneticsApril 1, 2019Hyo Sik Jang et al.hours. LIN28B and β-actin were detected using an anti-LIN28B antibody (Cell Signaling Technology, #4196) and an anti-ACTB mouse monoclonal antibody (GenScript, A00702), respectively. More details about the

(16) Lin28 and let-7 regulate the timing of cessation of murine nephrogenesisNature communicationsJanuary 11, 2019Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, et al.5-min incubation in xylene followed by mounting. Antibodies used: anti-LIN28B (1:250, Cell Signaling, #4196), anti-Six2 (1:250, Proteintech Group, #11562-1-AP), anti-Lef1 (1:250, Cell Signaling, #2230). Immunofluorescence

(17) Lin28 Signaling Supports Mammalian PNS and CNS Axon RegenerationCell reportsSeptember 4, 2018Wang XW, Li Q, Liu CM, Hall PA, Jiang JJ, Katchis CD, Kang S, Dong BC, Li S, Zhou FQ.,Cell Signaling Technology,Cat#5422S; RRID: AB_10697489 Rabbit polyclonal anti-hLin28b,Cell Signaling Technology,Cat#4196S; RRID: AB_2135047 Rabbit monoclonal anti-pS6 (Ser235/236),Cell Signaling Technology,Cat#4858S; RRID:

(18) Cyclic compressive loading activates angiotensin II type 1 receptor in articular chondrocytes and stimulates hypertrophic differentiation through a G‐protein‐dependent pathwayFEBS Open BioJune 1, 2018Fumihisa Nakamura, Ichiro Tsukamoto, Shinji Inoue, Kazuhiko Hashimoto, Masao Akagi

(19) TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progressionNature communicationsMay 10, 2018Ottaviani S, Stebbing J, Frampton AE, Zagorac S, Krell J, de Giorgio A, Trabulo SM, Nguyen VTM, Magnani L, Feng H, et al.(Santa Cruz, sc-25388, 1:500 dilution), SNAI1 (Santa Cruz, sc-28199, 1:500 dilution), LIN28B (Cell Signaling, #4196, 1:1000 dilution), LIN28A (Cell Signaling, #3978, 1:1000 dilution), SMAD2/3 (Cell Signaling, #8685,

(20) PCAF-mediated acetylation of Lin28B increases let-7 biogenesis in lung adenocarcinoma H1299 cellsBMC cancerJanuary 4, 2018Qu TT, Chen F, Wang J, Zhang YJ, Cheng MB, Sun WZ, Shen YF, Zhang Y.Antibodies to FLAG (F3165) and M2 (F2426) were purchased from Sigma (St. Louis, MO). Antibodies to Lin28B (4196) and acetyl lysine (9441) were purchased from Cell Signaling Technology (Beverly, MA). Plasmids, constructs,

Be the First to Write a Review!

LIN28B Antibody

LIN28B Antibody from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (43)

Reviews

LIN28B Antibody from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map