MSK1 (C27B2) Rabbit mAb 3489S from Cell Signaling Technology

Product Specs
ItemMSK1 (C27B2) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number3489S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
TargetMSK1
HostRabbit
NCBI Gene AliasesMSK1, MSPK1, RLPK
ClonalityMonoclonal
NCBI Full Gene Nameribosomal protein S6 kinase A5
Research AreaMAP Kinase Signaling
IsotypeIgG
CloneC27B2
Molecular Weight90

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) HIIT-induced lactate/GPR81 signaling with dual branches converging on ERK1/2 contributes to hippocampal synaptic remodeling and memory improvementFrontiers in Cell and Developmental BiologyJanuary 14, 2026Xuepeng Bian, Qinghui Shang, Lutao Zhu, Jun Liu, Min Wu, Jingjing Li, Shujie LouPKA (4782S, CST), RAP1 (2399S, CST), PKC (SC-80 Santa), PLC (14247S, CST), Raf1 (9422S, CST), MSK1 (3489S, CST), P90RSK (9355S, CST), ERK (4370T, CST), CREB (9197S, CST), c-Fos (2250S, CST), Zif268 (4154S,

(2) MSK1 promotes colorectal cancer metastasis by increasing Snail protein stability through USP5-mediated Snail deubiquitinationExperimental & Molecular MedicineApril 1, 2025Keun-Seok Hong, Ki-Jun Ryu, Hyemin Kim, Minju Kim, Seung-Ho Park, Taeyoung Kim, Jung Wook Yang, Cheol Hwangbo, Kwang Dong Kim, Young-Jun Park, et al.according to the manufacturer’s instructions. Primary antibodies used were: anti-MSK1 (Cell Signaling, no. 3489; 1:1,000), anti-phospho-MSK1(Thr581) (Cell Signaling, no. 9595; 1:1,000), anti-α-tubulin (Sigma-Aldrich,

(3) Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer’s diseaseNeuronJanuary 22, 2025Pourya Naderi Naderi Yeganeh, Sang Su Kwak, Mehdi Jorfi, Katjuša Koler, Thejesh Kalatturu, Djuna von Maydell, Zhiqing Liu, Kevin Guo, Younjung Choi, Joseph Park, et al.(T581),Cell Signaling Technologies,Cat. # 9595; RRID:AB_2181783 Anti-MSK1,Cell Signaling Technologies,Cat. # 3489; RRID:AB_2285349 Anti-phospho-MAPKAPK-2 (T222),Cell Signaling Technologies,Cat. # 3316; RRID:AB_2141311 Anti-MAPKAPK-2,Cell Signaling Technologies

(4) Impaired autophagy flux contributes to enhanced ischemia reperfusion injury in the diabetic heartAutophagy ReportsDecember 31, 2024Jialing Tang, Nanyoung Yoon, Keith Dadson, Hye Kyoung Sung, Yubin Lei, Thanh Q. Dang, Wing Yan Chung, Saher Ahmed, Ali A. Abdul-Sater, Jun Wu, et al.2772), cleaved Caspase 3 (1:1000, Cell Signaling, 9661), Bcl-2 (1:1000, Cell Signaling Technology, 3489), and β-tubulin (1:2000, Cell Signaling Technology, 2128), GAPDH (1:2000, Cell Signaling Technology,

(5) Ischemia-induced cardiac dysfunction is exacerbated in adiponectin-knockout mice due to impaired autophagy fluxClinical and translational scienceMarch 1, 2024Sung HK, Tang J, Jahng JWS, Song E, Chan YK, Lone AH, Peterson J, Abdul-Sater A, Sweeney G.Cell Signaling, #2772), cleaved Caspase 3 (1:1000, Cell Signaling, #9661), bcl‐2 (1:1000, Cell Signaling, #3489), and β‐actin (1:2000, ThermoFisher, #PA1‐46296) were used. The quantification of signals was performed

(6) Interruption of p38MAPK-MSK1-CREB-MITF-M pathway to prevent hyperpigmentation in the skinInternational Journal of Biological SciencesFebruary 17, 2024Song-Hee Kim, Jiyeon Lee, Jihye Jung, Ga Hyun Kim, Cheong-Yong Yun, Sang-Hun Jung, Bang Yeon Hwang, Jin Tae Hong, Sang-Bae Han, Jae-Kyung Jung, et al.(Cell Signaling Technology, 9252); anti-p-MSK1 (Cell Signaling Technology, 9595); anti-MSK1 (Cell Signaling Technology, 3489); anti-p-MKK3/6 (Cell Signaling Technology, 9236); anti-MKK3/6 (Cell Signaling Technology, 8535); anti-tyrosinase

(7) Synergistic anticancer effect by targeting CDK2 and EGFR–ERK signalingJournal of Cell BiologyJanuary 1, 2024Jinhuan Wu, Yuping Chen, Rui Li, Yaping Guan, Mu Chen, Hui Yin, Xiaoning Yang, Mingpeng Jin, Bingsong Huang, Xin Ding, et al.Abcam), anti-cyclinA2 (67955S; CST), anti-P-CDK substrate (9477S; CST), anti-RSK (9333S; CST), anti-MSK (3489S; CST), anti-Phospho-p90RSK (Ser380; 9341S; CST), anti-Phospho-MSK1 (Thr581; 9595S; CST), anti-HA-tag

(8) Exosomal miR-155-5p drives widespread macrophage M1 polarization in hypervirulent Klebsiella pneumoniae-induced acute lung injury via the MSK1/p38-MAPK axisCellular & Molecular Biology LettersNovember 13, 2023Yihan Xu, Chunying Zhang, Danni Cai, Rongping Zhu, Yingping Caoanti-ALIX (1:2000, Cat.E6P9B, CST), anti-TSG101 (1:2000, Cat.ab125011, Abcam), anti-MSK1 (1:500, Cat.3489S, CST), anti-DUSP1 (1:1000, Cat.ab138265, Abcam), anti-p-p38MAPK (1:1000, Cat.4511T, CST), anti-p38MAPK

(9) Dexmedetomidine Improves Anxiety-like Behaviors in Sleep-Deprived Mice by Inhibiting the p38/MSK1/NFκB Pathway and Reducing Inflammation and Oxidative StressBrain sciencesJuly 11, 2023Li J, Zhang H, Deng B, Wang X, Liang P, Xu S, Jing Z, Xiao Z, Sun L, Gao C, et al.and the corresponding primary antibodies (anti-p38: CST, 8690; anti-p-p38: CST, 4511; anti-MSK: CST, 3489S; anti-p-MSK: CST, 9595S; anti-NFκBp65: CST, 8242; anti-p-NFκBp65: CST, 3033T; anti-GAPDH: BOSTER, A00227-1)

(10) miRNA-132/212 Deficiency Disrupts Selective Corticosterone Modulation of Dorsal vs. Ventral Hippocampal MetaplasticityInternational Journal of Molecular SciencesMay 31, 2023Shima Kouhnavardi, Maureen Cabatic, M. Carmen Mañas-Padilla, Marife-Astrid Malabanan, Tarik Smani, Ana Cicvaric, Edison Alejandro Muñoz Aranzalez, Xaver Koenig, Ernst Urban, Gert Lubec, et al.Sirt1 (Cell Signaling Technology; USA, Cat. Nr. 2028); MSK1 (Cell Signaling Technology; USA, Cat. Nr. 3489); p-MSK1 (Cell Signaling Technology; USA, Cat. Nr. 9595); CDK5 (Cell Signaling Technology; USA, Cat.

(11) p38δ controls Mitogen- and Stress-activated Kinase-1 (MSK1) function in response to toll-like receptor activation in macrophagesFrontiers in cell and developmental biologyJanuary 1, 2023Díaz-Mora E, González-Romero D, Meireles-da-Silva M, Sanz-Ezquerro JJ, Cuenda A.phospho-p38MAPK (Thr180-Tyr182; #9211), total MK2 (#3042), phospho-MK2 (Thr334; #3042), total MSK1 (#3489), phospho-MSK1 (Thr581; #9595), phospho-c-Jun (Ser73; #9164) and phospho-IKKα/β (Ser176/180; #2697)

(12) Carbon dioxide inhibits COVID-19-type proinflammatory responses through extracellular signal-regulated kinases 1 and 2, novel carbon dioxide sensorsCellular and molecular life sciences : CMLSDecember 1, 2021Galganska H, Jarmuszkiewicz W, Galganski L.anti-phospho-ERK1/2 (Thr202/Tyr204), (1:1000, 42, 44 kDa, # 9101, RRID:AB_331646), anti-MSK1 (1:1000, 95 kDa, #3489, RRID:AB_2285349), anti-phospho-MSK1 (Thr581) (1:1000, 95 kDa, #9595, RRID:AB_2181783), anti-p38 (1:1000,

(13) Clofarabine induces ERK/MSK/CREB activation through inhibiting CD99 on Ewing sarcoma cellsPloS oneJanuary 1, 2021Sevim H, Çelik H, Düşünceli L, Ceyhan CS, Molotkova A, Nakazawa K, Graham GT, Petro JR, Toretsky JA, Üren A.described [17] using following primary antibodies; anti-ERK1/2 (#9107S), anti-pERK1/2 (#4370S), anti-MSK1 (#3489), anti-MSK2 (#3479), anti-CREB (#4820S), anti-pCREB (#9198S), anti-STAT-3 (#9139S), anti-pSTAT-3 (#9131S)

(14) Exercise-dependent increases in protein synthesis are accompanied by chromatin modifications and increased MRTF-SRF signallingActa physiologica (Oxford, England)September 1, 2020Solagna F, Nogara L, Dyar KA, Greulich F, Mir AA, Türk C, Bock T, Geremia A, Baraldo M, Sartori R, et al.P‐MKK3Ser189/MKK6Ser207 (#9231S), Phospho‐p38 MAPKThr180/Tyr182 (#9211S), P‐MSK1Thr581 (#9595S), MSK1 (#3489S), p38 MAPK (#9212S), Phospho‐AktSer473 (#4060S), Phospho‐S6Ser240/244 Ribosomal Protein (#5364S) were

(15) MicroRNA-130a Contributes to Type-2 Classical DC-activation in Sjögren's Syndrome by Targeting Mitogen- and Stress-Activated Protein Kinase-1Frontiers in immunologyJanuary 1, 2019Lopes AP, van Roon JAG, Blokland SLM, Wang M, Chouri E, Hartgring SAY, van der Wurff-Jacobs KMG, Kruize AA, Burgering BMT, Rossato M, et al.overnight at 4◦ C with antibodies recognizing mitogen- and stressactivated protein kinase-1 (MSK1) (#3489, rabbit anti-human, Cell Signaling Technology) and histone 3 (H3) (#9715, rabbit anti-human, Cell Signaling Technology

(16) Exclusive enteral nutrition protects against inflammatory bowel disease by inhibiting NF‑κB activation through regulation of the p38/MSK1 pathwayInternational journal of molecular medicineSeptember 1, 2018Yu T, Yu Q, Chen X, Zhou L, Wang Y, Yu C.TX, USA), and antibodies against ERK1/2 (9102s; 1:2,000), p-MSK1 (Thr581; 9595; 1:1,000) and MSK1 (3489; 1:2,000) were purchased from Cell Signaling Technology, Inc. (Danvers, MA, USA). IRDye 800-conjugated

(17) PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear TranslocationScientific reportsJune 18, 2018Davis TB, Yang M, Schell MJ, Wang H, Ma L, Pledger WJ, Yeatman TJ.

(18) Retinal Neuroprotection From Optic Nerve Trauma by Deletion of Arginase 2Frontiers in neuroscienceJanuary 1, 2018Xu Z, Fouda AY, Lemtalsi T, Shosha E, Rojas M, Liu F, Patel C, Caldwell RW, Narayanan SP, Caldwell RB.MA",1:500,Western blotting p-MSK1,9595,"Cell Signaling, Danvers, MA",1:500,Western blotting total MSK1,3489,"Cell Signaling, Danvers, MA",1:500,Western blotting NLRP3,15101,"Cell Signaling, Danvers, MA",1:500,Western blotting

(19) Mitogen- and Stress-Activated Protein Kinase 1 Regulates Status Epilepticus-Evoked Cell Death in the HippocampusASN neuroSeptember 1, 2017Choi YS, Horning P, Aten S, Karelina K, Alzate-Correa D, Arthur JSC, Hoyt KR, Obrietan K.(at 4℃) with a rabbit polyclonal total MSK1 antibody (1:500 dilution, Cell Signaling, catalog number: 3489) and with a mouse monoclonal anti-NeuN antibody (1:1,000 dilution, Millipore, Billerica, MA; catalog

(20) Secreted Protein Acidic and Rich in Cysteine (SPARC) Enhances Cell Proliferation, Migration, and Epithelial Mesenchymal Transition, and SPARC Expression is Associated with Tumor Grade in Head and Neck CancerInternational journal of molecular sciencesJuly 18, 2017Chang CH, Yen MC, Liao SH, Hsu YL, Lai CS, Chang KP, Hsu YL.Cell Signaling), anti-phospho Msk1 (1:1000, cat. no. 9591S, Cell Signaling), anti-Msk1 (1:1000, cat. no. 3489S, Cell Signaling), anti-phospho Rsk1 (1:1000, cat. no. 9335S, Cell Signaling), anti-Rsk1 (1:1000, cat.

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MSK1 (C27B2) Rabbit mAb

MSK1 (C27B2) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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MSK1 (C27B2) Rabbit mAb from Cell Signaling Technology

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