LDHA/LDHC (C28H7) Rabbit mAb 3558S from Cell Signaling Technology

Product Specs
ItemLDHA/LDHC (C28H7) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number3558S
Quantity100 µl
ApplicationsW, IHC-P
ReactivityH, R, Mk
HostRabbit
ClonalityMonoclonal
TargetLDH-A;LDH-C
NCBI Full Gene Namelactate dehydrogenase A, lactate dehydrogenase C
NCBI Gene AliasesPIG19, LDHX, HEL-S-133P, GSD11, LDH3, LDHM, CT32
Research AreaMetabolism
IsotypeIgG
CloneC28H7
Molecular Weight37

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Senescent Fibroblasts Drive Melanoma Progression Through GCP ‐2 Induced CREB Phosphorylation Enhancing GlycolysisAging CellNovember 19, 2025Abhijit Basu, Vida Farsam, Karmveer Singh, Diana Crisan, Nicolai Treiber, Lars Alexander Schneider, Margit Huber, Jennifer I. Engelmeyer, Björn Schumacher, Pallab Maity, et al.Signaling Technologies), (pCS1 #SC33397; Santacruz), (pPDH‐E1a #AP1062; Millipore), (PDHK1 #3820; LDHA/C #3558; ACO2 #6571; Cell signaling Technologies) and (Ki67; SP6; Thermo Scientific). Isotype IgG served as

(2) Follicular fluid-derived extracellular vesicles miR-34a-5p regulates granulosa cell glycolysis in polycystic ovary syndrome by targeting LDHAJournal of ovarian researchNovember 13, 2024Cui X, Lei X, Huang T, Mao X, Shen Z, Yang X, Peng W, Yu J, Zhang S, Huo P.muscle isozyme M2 (PKM2; #4053, 1:1,000 dilution; Cell Signaling Technology, Massachusetts, USA), LDHA (#3558, 1:1,000 dilution; Cell Signaling Technology), BAX (RT40051, 1:1,000 dilution; Abmart), BCL-2 (13-8800,

(3) Regulation of H9C2 cell hypertrophy by 14-3-3η via inhibiting glycolysisPLOS ONEJuly 22, 2024Sha Wan, Songhao Wang, Xianfei Yang, Yalan Cui, Heng Guan, Wenping Xiao, Fang LiuProteintech, Wuhan, China), Histone H3 (68345-1-Ig, Proteintech, Wuhan, China), and rabbit against LDHA (3558S, Cell Signaling Technology, Boston, USA), 14-3-3η (ab206292, Abcam, Cambridge, UK), actin (#4970, Cell Signaling Technology

(4) Proximal tubular FHL2, a novel downstream target of hypoxia inducible factor 1, is a protector against ischemic acute kidney injuryCellular and molecular life sciences : CMLSMay 30, 2024Wang Y, Kuang Z, Xing X, Qiu Y, Zhang J, Shao D, Huang J, Dai C, He W.NBP2-02272, Novus, USA), anti-PKM2 (1:1000; 4053, Cell Signaling Technology (CST), USA), anti-LDHA (1:1000; 3558, CST), anti-p-AKT (1:1000; 4060, CST), anti-AKT (1:1000; 9272, CST), anti-p53 (1:1000; 2524, CST), anti-cyclin

(5) Pan-cancer analysis implicates novel insights of lactate metabolism into immunotherapy response prediction and survival prognosticationJournal of Experimental & Clinical Cancer ResearchApril 25, 2024Dongjie Chen, Pengyi Liu, Xiongxiong Lu, Jingfeng Li, Debin Qi, Longjun Zang, Jiayu Lin, Yihao Liu, Shuyu Zhai, Da Fu, et al.follows:β-Actin Rabbit mAb (1:5000, Abclonal, #AC048).LDHA Rabbit mAb (1:1000, Cell Signaling Technology, #3558S). Flow cytometry and intracellular staining Cells were harvested, centrifuged, washed, and suspended

(6) Modulation of immune checkpoint regulators in interferon γ induced urothelial carcinoma and activated T-lymphocyte cells by cytostaticsGenes and immunityJune 1, 2023Hänze J, Schulte-Herbrüggen J, Hofmann R, Hegele A.antibodies were as follows: PD-L1 #13684 (Cell signaling), PD-1, host goat (AF1086, R&D Systems); (LDHA #3558, Cell signaling). Data were analysed with MS-Office Excel and Graphpad Prism Version 9.50. Results Screening

(7) LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancerJournal for immunotherapy of cancerMarch 1, 2023Zhao T, Liu S, Hanna NH, Jalal S, Ding X, Wan J, Yan C, Du H.antibodies against metabolic molecules including G6PD (D5D2, catalog no 12 263S), LDH (C28H7, catalog no 3558S), PDH (catalog no 2784S), and GLUD (D9F7P, catalog no 12 793S) (Cell Signaling, Beverly, Massachusetts,

(8) Resveratrol regulates insulin resistance to improve the glycolytic pathway by activating SIRT2 in PCOS granulosa cellsFrontiers in NutritionJanuary 18, 2023Aihong Liang, Wenmao Zhang, Qian Wang, Lan'e Huang, Jiaming Zhang, Duo Ma, Ke Liu, Shiyu Li, Xi Chen, Shan Li, et al.(1:1,000, #4053; Cell Signaling Technology, USA), HK2 (1:1000, A0994; ABclonal, China), LDHA (1:1000, #3558; Cell Signaling Technology, USA), SIRT2 (1:1000, A12575; ABclonal, China), and GAPDH (1:1,000, #97166;

(9) Lysosomal acid lipase, CSF1R, and PD-L1 determine functions of CD11c+ myeloid-derived suppressor cellsJCI insightSeptember 8, 2022Zhao T, Liu S, Ding X, Johnson EM, Hanna NH, Singh K, Sen CK, Wan J, Du H, Yan C.non-fluorescence-conjugated antibodies against metabolic molecules including G6PD (D5D2, catalog 12263S), LDH (C28H7, catalog 3558S), PDH (catalog 2784S), and GLUD (D9F7P, catalog 12793S) (Cell Signaling Technology), at 4°C overnight.

(10) Mogroside V Improves Follicular Development and Ovulation in Young-Adult PCOS Rats Induced by Letrozole and High-Fat Diet Through Promoting GlycolysisFrontiers in endocrinologyJanuary 1, 2022Huang L, Liang A, Li T, Lei X, Chen X, Liao B, Tang J, Cao X, Chen G, Chen F, et al.(RK21203) was purchased from ABclonal Technology Co., Ltd. (Wuhan, China). LDHA (C28H7) rabbit mAb (#3558), hexokinase II (HK2) rabbit mAb (#2867) and PKM2 (D78A4) XP® mAb (#4053) were purchased from Cell Signaling Technology

(11) Colorectal Cancer Progression Is Potently Reduced by a Glucose-Free, High-Protein Diet: Comparison to Anti-EGFR TherapyCancersNovember 19, 2021Skibbe K, Brethack AK, Sünderhauf A, Ragab M, Raschdorf A, Hicken M, Schlichting H, Preira J, Brandt J, Castven D, et al.µg/mL Anti-Tom20 (D8T4N) (#42406),rabbit,"Cell Signaling, Danvers, MA, USA",1:1000 a Anti-LDHA/C (C28H7) (#3558),rabbit,"Cell Signaling, Danvers, MA, USA",1:1000 a Anti-CD3ε (ab5690),rabbit,"Abcam, Cambridge, UK",1

(12) Translatome and Transcriptome Profiling of Hypoxic-Induced Rat CardiomyocytesMolecular therapy. Nucleic acidsDecember 4, 2020Shen Z, Zeng L, Zhang Z.(ab231260, Abcam, Cambridge, MA, USA), GLUT1 (21829-1, Proteintech Group, Rosemont, IL, USA), LDHA (#3558, Cell Signaling Technology), BNIP3 (#3769, Cell Signaling Technology), ADRB2 (#13096-1, Proteintech

(13) A glycolytic shift in Schwann cells supports injured axonsNature neuroscienceOctober 1, 2020Babetto E, Wong KM, Beirowski B.Cell Signaling, 4053), PFKFB3 D7H4Q (1:200, Cell Signaling, 13123), LDHA/LDHC C28H7 (1:200, Cell Signaling, 3558), LDHB (1:200, Proteintech, 14824-1-AP), Glut1 D3J3A (1:200, Cell Signaling, 12939), PDHK1 C47H1 (1:100,

(14) Sodium-glucose cotransporter 2 inhibition suppresses HIF-1α-mediated metabolic switch from lipid oxidation to glycolysis in kidney tubule cells of diabetic miceCell death & diseaseMay 22, 2020Cai T, Ke Q, Fang Y, Wen P, Chen H, Yuan Q, Luo J, Zhang Y, Sun Q, Lv Y, et al.USA), anti-CPT1α (ab128568, Abcam), anti-ACADL (ab196655, Abcam), anti-HK2 (ab76959, Abcam), anti-LDH (3558, Cell Signaling Technology, Danvers, MA, USA), anti-PDK1 (ab110025, Abcam), anti-HIF-1α (ab1, Abcam),

(15) Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiationCell death & diseaseMay 11, 2020Yuan Q, Miao J, Yang Q, Fang L, Fang Y, Ding H, Zhou Y, Jiang L, Dai C, Zen K, et al.Abcam), PKM1 (7067 S, CST), p-PKM2 (3827 S, CST), PKM2 (4053 S, CST), PKLR (ab137787, Abcam), LDHA (3558 S, CST), PGC-1α (ab54481, Abcam), TFAM (ab131607, Abcam), OPA-1 (ab42364, Abcam), DRP-1 (ab184247, abcam),

(16) In vivo glucoregulation and tissue-specific glucose uptake in female Akt substrate 160 kDa knockout ratsPloS oneJanuary 1, 2020Zheng X, Arias EB, Qi NR, Saunders TL, Cartee GD.anti-phospho Akt2Ser474 (pAkt2 Ser474, #8599), anti-SGLT1 (#5042), ACC (#3676), pACCSer79 (#3661), anti-LDH (#3558), and anti-rabbit IgG horseradish peroxidase conjugate (#7074) were from Cell Signaling Technology (Danvers,

(17) Effects of β-caryophyllene on arginine ADP-ribosyltransferase 1-mediated regulation of glycolysis in colorectal cancer under high-glucose conditionsInternational Journal of OncologyJuly 27, 2018Li Zhou, Mu-Lu Zhan, Yi Tang, Ming Xiao, Ming Li, Qing-Shu Li, Lian Yang, Xian Li, Wen-Wen Chen, Ya-Lan Wang(ser473) (#4060T), mTOR (#2983P), p‑mTOR (ser2448) (#5536T), PDK1 (#3062T), c‑Myc (#5605T), LDHA (#3558S), B-cell lymphoma 2-associated X protein (Bax) (#14796S) and cleaved caspase‑3 (#9664T) (all from Cell Signaling Technology

(18) A DGKζ-FoxO-ubiquitin proteolytic axis controls fiber size during skeletal muscle remodelingScience signalingMay 15, 2018You JS, Dooley MS, Kim CR, Kim EJ, Xu W, Goodman CA, Hornberger TA.anti–phospho-Akt (Thr308; #9275), anti-Akt (#9272), anti-FoxO3a (#2497), anti-HA (#3724), anti-GFP (#2555), and anti-LDHA (#3558) antibodies were purchased from Cell Signaling. Rabbit anti-phospho-p70S6k (Thr389), anti-DGKδ (sc66860),

(19) Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesisOncotargetOctober 31, 2017Cigliano A, Pilo MG, Li L, Latte G, Szydlowska M, Simile MM, Paliogiannis P, Che L, Pes GM, Palmieri G, et al.anti-ACAC (# 3662), anti-DDK (# 14793), anti-HKII (# 2867), anti-LDHA/C (Cell Signaling Technology Inc.; # 3558), anti-ODC (# sc-390366), anti-NRF1 (Santa Cruz Biotechnology; # sc-365651), anti-c-Myc (# sc-40), and

(20) Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines in vitro and AKT-driven hepatocarcinogenesis in miceOncotargetAugust 15, 2017Antonio Cigliano et al.total-AKT (#9272), anti-ACAC (#3662), anti-ACLY (13390), anti-PPARγ (#2435), anti-ALDOA (#3188), LDHA/C (#3558), SCD1 (#2794), anti-phosphorylated NDRG1 (#5482) (Cell Signaling Technology Inc.), and V5 (#81594;

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LDHA/LDHC (C28H7) Rabbit mAb

LDHA/LDHC (C28H7) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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LDHA/LDHC (C28H7) Rabbit mAb from Cell Signaling Technology

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