Fig 1: Mast cells in peritoneal fluid from mice induced with endometriosis. Mature mast cells were CD117+, FCERIa+, CD11b- (A). MCp were CD117+, FCERIa+, CD11b-, integrin β7+, SSClo (A). The estrogen treated sham operated group had significantly higher mast cell frequency within the CD45+ population compared to the untreated EMS group (p= 0.0256) (B). The E2 EMS group had significantly lower peritoneal mast cells than both E2 sham and untreated sham groups (p= 0.0057, 0.0414) (B). Frequency of MCp in the CD45+ population was significantly higher in EMS-induced mice vs. E2-treated EMS and E2-sham, untreated sham groups (p= 0.0172, 0.0109, 0.0479) (C).