Phospho-LKB1 (Ser428) (C67A3) Rabbit mAb 3482S from Cell Signaling Technology

Product Specs
ItemPhospho-LKB1 (Ser428) (C67A3) Rabbit mAb
CompanyCell Signaling Technology
Price $401.00 Inquire
Catalog Number3482S
Quantity100 µl
ApplicationsW
ReactivityH, M, R, Mk
TargetLKB1 (Ser428) phosphate
ModificationsLKB1 (Ser428) phosphate
HostRabbit
NCBI Gene AliasesLKB1, PJS, hLKB1
ClonalityMonoclonal
NCBI Full Gene Nameserine/threonine kinase 11
Research AreaMetabolism
CloneC67A3
Molecular Weight54

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Polydatin Relieves Airway Remodeling by Inhibiting P2X7R-NLRP3-Mediated Excessive Autophagy in AsthmaImmun Inflamm DisApril 5, 2026Guangxing Li, Liangchang Li, Zhiguang Wang, Yihua Piao, Yilan Song, Li Li, Chang Xu, Xiaowan Li, Guanghai YanAbcam), MMP‐9 (ab38898; Abcam), LC3‐I/II (ABC929; Sigma), Beclin‐1 (ab62557; Abcam), LKB1 (Ser428; #3482; CST), LKB1 (#3047; CST), AMPKα (Thr172; #2535; CST), AMPKα (#5831; CST), mTOR (Ser2448; #2971; CST),

(2) Targeting mitochondrial phosphatidylethanolamine alters mitochondrial metabolism and proliferation in hepatocellular carcinomaOncogenesisDecember 8, 2025Melina C. Mancini, Cameron P. McCall, Robert C. Noland, Wagner S. Dantas, Timothy D. HedenCell Signaling Technology), liver kinase B1 (LKB1, 3047, Cell Signaling Technology), phosphorylated LKB1S428 (3482, Cell Signaling Technology), adenosine monophosphate activated protein kinase (AMPK, 2532, Cell Signaling Technology

(3) Human plasma-derived eNAMPT-containing extracellular vesicles promote NAD+ biosynthesis and thermogenesis in micenpj AgingNovember 24, 2025Kiyoshi Yoshioka, Takumi Sugimoto, Mamoru Oyabu, Naoki Ito, Aoi Kodama, Yasutomi Kamei, Shin-ichiro Imai(NIH). The following primary antibodies were used: NAMPT (A300-372A, Bethyl), Phospho(Ser428)-LKB1 (#3482), LKB1 (#3047), Phospho(Thr172)-AMPKα (#2535), AMPKα (#2532, Cell Signaling Technology), Transferrin

(4) Autoimmune disease risk gene ANKRD55 promotes TH17 effector function through metabolic modulationJournal of Experimental MedicineNovember 3, 2025Jinjin Xu, Lingjia Kong, Elizabeth A. Creasey, Sneha Rath, Lei Deng, Julian Avila-Pacheco, Chenhao Li, Blayne A. Oliver, Tyler T. Dao, Angela R. Shih, et al.(Xu et al., 2023). Antibodies used were: phospho-LKB1 (Ser428) (Cell Signaling Technology, catalog 3482S, RRID: AB_2198321), LKB1 (D60C5) (Cell Signaling Technology, catalog 3047, RRID: AB_2198327), MTHFD2 polyclonal antibody

(5) The antiadipogenic effect of the pentacyclic triterpenoid isoarborinol is mediated by LKB1-AMPK activationPLOS OneSeptember 3, 2025Yesenia Arcos-Reyes, Gildardo Rivera, Laurence A. Marchat, Juan Salas-Benito, Gilberto Mandujano-Lázaro, Moisés Monzón-Gualito, Esther Ramírez-MorenomAb #50081(1:5000); AMPKα (D5A2) Rabbit mAb #5831 (1:5000); Phospho-LKB1 (Ser428) (C67A3) Rabbit mAb #3482 (1:5000); LKB1 (C60C5) Rabbit mAb #3047 (1:5000); β-Actin (13E5) Rabbit mAb #4970 (1:1000). Finally,

(6) Energy stress-induced PKCζ S-glutathionylation is essential for LKB1 cytoplasmic translocation and AMPK activationLife MetabolismJuly 16, 2025Junjie Fei, Shuhan Yu, Mingzhe Xu, Yang Liu, Guoqiang Wang, Xueqing Li, Xinyue Yu, Yifan Zhang, Wenhua Zhang, Yang Wang, et al.Santa Cruz (USA). Antibodies for pAMPK (#2535, 1:1000), pACC (#3661,1:1000), LKB1 (#3050, 1:1000), pLKB1 (#3482, 1:1000), HA (#3724, 1:1000), and Flag (#117935, 1:1000) were purchased from Cell Signaling Technology

(7) PTEN deficiency in postnatally developing Purkinje cells disrupts metabolic signaling, leading to dendritic abnormalities and sex-specific behavioral deficitsSci RepJuly 8, 2025Lindsay J. Walsh, Izabella M. Espinal-San Miguel, Ana V. Rodriguez, Ursula M. Peña, Kiley E. Flynn, Will C. Remillard, Siena R. Brazier, Natalia I. Anderson, Aidan J. Clark, Tiffany A. De Varona, et al.Sigma-Aldrich, MAB3418), rabbit anti-pAMPK (1:200, Cell Signalling, #4060), rabbit anti-pLKB1 (1:200, #3482) and NeuroTrace (Invitrogen). Cytochrome c oxidase (COX) histochemistry COX activity in the ML of

(8) Inhibition of serotonin-Htr2b signaling in skeletal muscle mitigates obesity-induced insulin resistanceExperimental & Molecular MedicineJune 2, 2025Suhyeon Park, Hyeongseok Kim, Soyeon Shin, Yeongmin Kim, Yunwon Kang, Hye-Na Cha, So-Young Park, Sangkyu Park, Chang-Myung Oh(Ser1101) (Cell Signaling Technology, #2385), rabbit Phospho-LKB1 (Ser428) (Cell Signaling Technology, #3482), rabbit LKB1 (Cell Signaling Technology, #3047), rabbit SIRT1 (Abcam, ab189494), rabbit TPH1 (Invitrogen,

(9) Acinetobacter baumannii OmpA hinders host autophagy via the CaMKK2-reliant AMPK-pathwaymBioApril 9, 2025Kyungho Woo, Dong Ho Kim, Ho-Sung Park, Man Hwan Oh, Je Chul Lee, Chul Hee Choirabbit anti-p-CaMKK2 (Cell Signaling Technology, 12818), rabbit anti-p-LKB1 (Cell Signaling Technology, 3482), rabbit anti-β-actin (Cell Signaling Technology, 4970), rabbit anti-p-ULK Ser317 (Invitrogen, PA5-104556),

(10) Liver TET1 promotes metabolic dysfunction-associated steatotic liver diseaseEMBO Molecular MedicineMarch 31, 2025Hongze Chen, Muhammad Azhar Nisar, Joud Mulla, Xinjian Li, Kevin Cao, Shaolei Lu, Katsuya Nagaoka, Shang Wu, Peng-Sheng Ting, Tung-Sung Tseng, et al.antibody (1:1000),Cell Signaling Technology®,3050S pLKB1 antibody (1:1000),Cell Signaling Technology®,3482S 5-methylcytosine antibody (1:1000),Active Motif,61479 "5-hydroxylmethylcytosine antibody (1:10,000)",Active Motif

(11) Isoquercitrin Attenuates Oxidative Liver Damage Through AMPK-YAP Signaling: An Integrative In Silico, In Vitro, and In Vivo StudyInt J Mol SciMarch 18, 2025So-Hyun Kwon, Won-Yung Lee, Young Woo Kim, Kwang Suk Ko, Seon Been Bak, Sun-Dong Parkanti-poly (ADP-ribose) polymerase (PARP, #9542), anti-procaspase 3, anti-phospho liver kinase B1 (p-LKB1, #3482), liver kinase B1 (LKB1, #3050), and Bcl-xL were purchased from Cell Signaling Technology (Beverly,

(12) A highland-adaptation variant near MCUR1 reduces its transcription and attenuates erythrogenesis in TibetansCell GenomMarch 12, 2025Ping J, Liu X, Lu Y, Quan C, Fan P, Lu H, Li Q, Wang C, Zhang Z, Liu M, et al.Cell Signaling Technology, USA), LKB1 (#3047; Cell Signaling Technology, USA), phosphorylated LKB1 (p-LKB1, Ser428; #3482; Cell Signaling Technology, USA), CAMKK2 (#16810; Cell Signaling Technology, USA), phosphorylated CAMKK2

(13) A CRISPR-edited isoform of the AMPK kinase LKB1 improves the response to cisplatin in A549 lung cancer cellsJournal of Biological ChemistryFebruary 13, 2025Matheus Brandemarte Severino, Ana Paula Morelli, Isadora Carolina Betim Pavan, Mariana Camargo Silva Mancini, Mariana Marcela Góis, Rafael Junqueira Borges, Renata Rosseto Braga, Luiz Guilherme Salvino da Silva, Nathalia Quintero-Ruiz, Maíra Maftoum Costa, et al.levels of interest proteins. Primary antibodies: LKB1 (Cell signaling, #3050), pLKB1 (Cell signaling, #3482), AMPK (Cell signaling #5831), pAMPK (Cell signaling #50081), p62 (Cell signaling #50081), LC3B I/II

(14) Mammalian mitochondrial inorganic polyphosphate (polyP) and cell signaling: Crosstalk between polyP and the activity of AMPKMolecular MetabolismJanuary 1, 2025Renata T. Da Costa, Anna Nichenko, Matheus M. Perez, Malgorzata Tokarska-Schlattner, Sheida Kavehmoghaddam, Vedangi Hambardikar, Ernest R. Scoma, Erin L. Seifert, Uwe Schlattner, Joshua C. Drake, et al.Massachusetts, USA).",CST-9272,Anti-Akt "Cell signaling Technology(Danvers, Massachusetts, USA).",CST-3482,Anti-S428pLKB1 "Cell signaling Technology(Danvers, Massachusetts, USA).",CST-2083,Anti-S792pRaptor "Cell

(15) β-catenin-inhibited Sumoylation modification of LKB1 and fatty acid metabolism is critical in renal fibrosisCell Death & DiseaseOctober 22, 2024Shuangqin Chen, Jiemei Li, Ye Liang, Meijia Zhang, Ziqi Qiu, Sirui Liu, HaoRan Wang, Ye Zhu, Shicong Song, Xiaotao Hou, et al.anti-LKB1 (Santa Cruz Biotechnology, Cat. #sc-32245, 1:1000), anti-p-LKB1 (Cell Signaling Technology, Cat. #3482s, 1:1000), anti-AMPKα (Cell Signaling Technology, Cat. #2532s, 1:1000), anti-p-AMPKα (Cell Signaling Technology

(16) Exercise activates AMPK in mouse and human pancreatic islets to decrease senescenceNature MetabolismSeptember 24, 2024Priscila Carapeto, Kanako Iwasaki, Francesko Hela, Jiho Kahng, Ana B. Alves-Wagner, Roeland J. W. Middelbeek, Michael F. Hirshman, Guy A. Rutter, Laurie J. Goodyear, Cristina Aguayo-Mazzucato,Cell Signaling Technology,2947 Anti-p16 ARC,1:1000,Abcam,Ab51243 Phospho LKB1 (Ser428),1:1000,Cell Signaling Technology,3482 Lkb1,1:1000,Cell Signaling Technology, Beta actin (8H10D10),1:1000,Cell Signaling Technology,3700 Monoclonal

(17) Hygrothermal stress increases malignant arrhythmias susceptibility by inhibiting the LKB1-AMPK-Cx43 pathwayScientific ReportsFebruary 29, 2024Jianing Chi, Ningxia Wu, Pengfei Li, Jiaman Hu, Hua Cai, Cailong Lin, Yingying Lai, Han Yang, Jianyu Huang, Min Li, et al.anti-thr172-phosphorylated AMPK (1:1000, 2535T, CST), anti-total AMPK (1:1000, 2532S, CST), anti-lkb1 (1:1000, 3482S, CST), and anti-GAPDH (1:5000, ab9485, Abcam). After that, the membranes were gently washed using Tris-buffered

(18) Developmental metformin exposure does not rescue physiological impairments derived from early exposure to altered maternal metabolic state in offspring miceMolecular MetabolismJanuary 1, 2024Lídia Cantacorps, Jiajie Zhu, Selma Yagoub, Bethany M. Coull, Joanne Falck, Robert A. Chesters, Katrin Ritter, Miguel Serrano-Lope, Katharina Tscherepentschuk, Lea-Sophie Kasch, et al.(Thr172),Rabbit,1:1000,Cell Signaling Technologies,#2535 phospho-LKB1 (Ser428),Rabbit,1:1000,Cell Signaling Technologies,#3482 phospho-mTOR (Ser2448),Rabbit,1:1000,Cell Signaling Technologies,#2971 β-Actin,Mouse,1:2500,Santa Cruz Biotechnology

(19) Physical exercise attenuates age-related muscle atrophy and exhibits anti-ageing effects via the adiponectin receptor 1 signallingJournal of cachexia, sarcopenia and muscleAugust 1, 2023Chen YL, Ma YC, Tang J, Zhang D, Zhao Q, Liu JJ, Tang HS, Zhang JY, He GH, Zhong CH, et al.(Ser511) (#12818, Cell Signaling), anti‐CaMKKβ (11549‐1‐AP, Proteintech), anti‐phospho‐LKB1 (Ser428) (#3482, Cell Signaling), anti‐LKB1 (#3047, Cell Signaling) and anti‐p62/SQSTM1 (#sc‐48402, Santa Cruz Biotechnology,

(20) Cannabinoid receptor agonist attenuates angiotensin II–induced enlargement and mitochondrial dysfunction in rat atrial cardiomyocytesFrontiers in PharmacologyApril 11, 2023Danielle I. Altieri, Yoram Etzion, Hope D. Andersonfor phospho-AMPKα (Thr172) (1:1000, cat. 2535), AMPKα (1:1000, cat. 2603), phospho-LKB1 (1:1000, cat. 3482), LKB1 (1:1000, cat. 3047) and Abcam (Toronto, Ontario) connexin 43 (1:7500, cat. ab11370), CB1R (1:500,

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Phospho-LKB1 (Ser428) (C67A3) Rabbit mAb

Phospho-LKB1 (Ser428) (C67A3) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-LKB1 (Ser428) (C67A3) Rabbit mAb from Cell Signaling Technology

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