Sox2 (C70B1) Rabbit mAb 3728S from Cell Signaling Technology

Product Specs
ItemSox2 (C70B1) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number3728S
Quantity100 µl
ApplicationsW, IHC-P
ReactivityM
TargetSox2
HostRabbit
NCBI Gene AliasesANOP3, MCOPS3
ClonalityMonoclonal
NCBI Full Gene NameSRY-box transcription factor 2
Research AreaDevelopmental Biology
CloneC70B1
Molecular Weight35

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) A MYC family switch: L-MYC drives and maintains neuroendocrine lineage programs in prostate cancerNeoplasiaApril 17, 2026Jeyaluxmy Sivalingam, Kaleigh Ballagh, Kyung Hyun Cho, Yingli Shi, Lin Li, Preston Barron, Michael S. Lan, Omar E Franco, Xiuping YuCell Signaling Technology), MYCN (#51705S; Cell Signaling Technology), MYC (#9402S; Cell Signaling Technology), SOX2 (#3728S; Cell Signaling Technology), ASCL1 (556604; BD Pharmingen), AR (#5153S; Cell Signaling Technology),

(2) CASC19 stabilization by ALYREF via m5C modification and its impact on SCD in colorectal cancer cell aggressiveness and stemnessCell & BioscienceMarch 7, 2026Li Zhao, Rongjun Xie, Li Li, Xianzhou Lu, Li Wang, Hui Wang, Longfei LiuH₂O₂, the sections were incubated with primary antibodies against ALYREF (ab6141, 1:500, Abcam), SOX2 (#3728, 1:100, CST, USA), Ki67 (#9449, 1:100, CST), and Bcl-2 (#15071, 1:100, CST) at 4 °C overnight. The next

(3) LPLAT11/MBOAT7-driven phosphatidylinositol remodeling ensures radial glial cell integrity in developing neocortexiScienceNovember 27, 2025Yuki Ishino, Yusuke Kishi, Taiga Iwama, Naohiro Kuwayama, Hiroyuki Arai, Yukiko Gotoh, Junken Aoki, Nozomu KonoAB_2341188 Rabbit anti-caspase-3,Cell Signaling,Cat# 9662S; RRID: AB_331439 Rabbit anti-Sox2,Cell Signaling,Cat# 3728S; RRID: AB_2194037 Mouse anti-phospho-Histone H3,Cell Signaling,Cat# 9706S; RRID: AB_331748 Mouse anti-Sox2,Santa Cruz Biotechnology

(4) Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiationCancer CellMay 12, 2025Mona Teng, Jiacheng Guo, Xin Xu, Xinpei Ci, Yulin Mo, Yakup Kohen, Zuyao Ni, Sujun Chen, Wang Yuan Guo, Martin Bakht, et al.cat. #904804), Ncam1 (Proteintech, cat. #14255-1-AP), Chga (Abcam, cat. #ab15160), Sox2 (CST, cat. #3728S), NKX2-1/Ttf-1 (Abcam, cat. #76013), and Ki67 (CST, cat. #12202) antibodies were used for IHC stainings.

(5) IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing NeocortexAdvanced ScienceMarch 7, 2025Yuqing Lv, Wenzheng Zou, Lin Li, Shukui Zhang, Jiaqi Liang, Jiali Pu, Jianwei Jiaocompounds and the pulse‐labeling procedure. Antibodies Rabbit anti‐SOX2 (Cell Signaling Technology Cat# 3728S; RRID: AB_2194037); Rabbit anti‐IFITM2 (Proteintech Cat# 12769‐1‐AP; RRID: AB_2122089); Mouse anti‐IFITM2

(6) Compromised cell competition exhausts neural stem cells poolCell ProliferationDecember 1, 2024Chenxiao Li, Mengtian Zhang, Yushan Du, Shuang Liu, Da Li, Shukui Zhang, Fen Ji, Jingjing Zhang, Jianwei Jiao(Abcam ab128874, Rabbit, 1:200); Tbr2(Abcam, ab23345, Rabbit, 1:1000); Sox2 (Cell Signaling Technology, 3728 s, Rabbit, 1:1000); GFAP (Sigma, G6171, Mouse, 1:1000); cleaved Casp3 (Cell Signaling Technology, 9664

(7) Unveiling novel double-negative prostate cancer subtypes through single-cell RNA sequencing analysisnpj Precision OncologyAugust 2, 2024Siyuan Cheng, Lin Li, Yunshin Yeh, Yingli Shi, Omar Franco, Eva Corey, Xiuping YuA4357), MMP7 (abclonal, A0695), CK5 (BioLegend, 905904), CK8 (BioLegend, 904801), SOX2 (Cell signaling, 3728), FOXA2 (Abcam, 108422). IHC staining was performed using a Vectastain elite ABC peroxidase kit (Vector Laboratories

(8) Olfactory bulb anomalies in KBG syndrome mouse model and patientsBMC MedicineApril 15, 2024Kara Goodkey, Anita Wischmeijer, Laurence Perrin, Adrianne E. S. Watson, Leenah Qureshi, Duccio Maria Cordelli, Francesco Toni, Maria Gnazzo, Francesco Benedicenti, Monique Elmaleh-Bergès, et al.RRID:AB_2236897, 1:400), and anti-SOX2 (Novus Bio, AF2018, RRID:AB_355110, 1:1000 or Cell Signaling, 3728S, RRID:AB_2194037, 1:1500). Secondary antibodies: anti-goat-555 (Jackson, 705–165-147, RRID:AB_2307351,

(9) USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticityMolecular cancerDecember 13, 2023Kwon J, Zhang J, Mok B, Allsup S, Kim C, Toretsky J, Han C.sc-514416) 1:600, NKX2-1 (Abcam, Cat# ab76013) 1:2000, SPC (Abcam, Cat# ab211326) 1:500, SOX2 (CST, Cat# 3728) 1:400, Cytokeratin 5 (Thermo Fisher Scientific, Cat# MA5-17057) 1:2000, MYC (Abcam, Cat# ab32072) 1:400.

(10) Curcumin protects from LPS-induced activation of astrocytes via AMPK pathwayNeuroReportOctober 4, 2023Jing Cheng, Yu Zhou, Haowen Qiao, Hongxiang Jiang, Yanqin FanAMPKα (Cell Signaling Technology, 2532), LC3I/II (Sigma, ABC929), Beclin-1 (Cell Signaling Technology, 3728), P62 (Cell Signaling Technology, 5114), GFAP (Cell Signaling Technology, 80788), MMP2 (Cell Signaling Technology

(11) TIMP3 promotes the maintenance of neural stem-progenitor cells in the mouse subventricular zoneFrontiers in NeuroscienceJune 28, 2023Lingyan Fang, Takaaki Kuniya, Yujin Harada, Osamu Yasuda, Nobuyo Maeda, Yutaka Suzuki, Daichi Kawaguchi, Yukiko Gotohanti-Ki67 (1:500, Agilent Cat# M7249, RRID:AB_2250503), anti-Sox2 (1:200, Cell Signaling Technology Cat# 3728, RRID:AB_2194037; 1:500, Santa Cruz Biotechnology Cat# sc-17320, RRID:AB_2286684), anti-S100β (1:200,

(12) Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brainCell proliferationMay 1, 2023Wang Y, Su L, Wang W, Zhao J, Wang Y, Li S, Liu Y, Chai R, Li X, Teng Z, et al.B‐1205); anti‐GFAP (Dako, Z0334); anti‐GFAP (Sigma, G6171); anti‐SOX2 (Cell Signalling Technology, 3728s); anti‐Tbr1 (Abcam; ab31940); anti‐GLAST (Proteintech, 20785‐1‐AP); anti‐S100𝛽 (Abcam, ab52642); anti‐MAP2

(13) c-Abl tyrosine kinase down-regulation as target for memory improvement in Alzheimer's diseaseFrontiers in aging neuroscienceJanuary 1, 2023León R, Gutiérrez DA, Pinto C, Morales C, de la Fuente C, Riquelme C, Cortés BI, González-Martin A, Chamorro D, Espinosa N, et al.O/N with primary antibody anti-WO2 (Millipore, MABN10), NeuN (ab177487, Abcam), Sox2 (Cell Signaling, 3728S), Doublecortin (Santa Cruz Biotechnology, sc-271,390) or GFAP (GA5, Cell Signaling, 3670S) (all 1:1000

(14) Iron commensalism of mesenchymal glioblastoma promotes ferroptosis susceptibility upon dopamine treatmentCommunications biologyJune 16, 2022Vo VTA, Kim S, Hua TNM, Oh J, Jeong Y.(sc-376088), TH (sc-25269), PAH (sc-271258), and DDC (sc-293287); from Cell Signaling Technology for SOX2 (#3728), CD44 (#3570), pSrc (#6943), Src (#2108), pSTAT3 (#9131), STAT3 (#9139), pERK (#9101 S), ERK (#9102

(15) High replication stress and limited Rad51-mediated DNA repair capacity, but not oxidative stress, underlie oligodendrocyte precursor cell radiosensitivityNAR cancerJune 1, 2022Berger ND, Brownlee PM, Chen MJ, Morrison H, Osz K, Ploquin NP, Chan JA, Goodarzi AA.reagents Primary antibodies were Nestin (1:200, Millipore Sigma, MAB353), Sox2 (1:200, Cell Signaling Technology #3728S), Olig2 (1:500, Abcam ab109186), PDGFRα (1:200, Cell Signaling Technology #3174S), NG2 (1:500, Millipore Sigma

(16) Endothelial Cells Mediated by UCP2 Control the Neurogenic-to-Astrogenic Neural Stem Cells Fate Switch During Brain DevelopmentAdvanced science (Weinheim, Baden-Wurttemberg, Germany)June 1, 2022Wang W, Su L, Wang Y, Li C, Ji F, Jiao J.anti‐biotinylated IsolectinB4(Vector Laboratories, B‐1205, 1:600); anti‐SOX2 (Cell Signaling Technology, 3728s, Rabbit, 1:1000); anti‐Tbr2(Abcam, ab23345, Rabbit, 1:1000); anti‐GFAP (Dako, Z0334, Rabbit, 1:3000);

(17) In vivo partial cellular reprogramming enhances liver plasticity and regenerationCell reportsApril 26, 2022Hishida T, Yamamoto M, Hishida-Nozaki Y, Shao C, Huang L, Wang C, Shojima K, Xue Y, Hang Y, Shokhirev M, et al.were used for IHC: anti-GFP (Abcam, 6673, 1:400; Clontech, JL-8, 1:200); anti-Klf4 (Cell signaling, 3728, 1:200); anti-Ki67 (Cell signaling, 12,202, 1:200); anti-Sox9 (Abcam, 185230, 1:100); anti-Alb (R&D,

(18) Impaired KDM2B-mediated PRC1 recruitment to chromatin causes defective neural stem cell self-renewal and ASD/ID-like behaviorsiScienceFebruary 18, 2022Gao Y, Duque-Wilckens N, Aljazi MB, Moeser AJ, Mias GI, Robison AJ, Zhang Y, He J.for 30 min after washing with PBS. Tissue sections were then incubated with rabbit anti-SOX2 (1:200, 3728, Cell Signaling technology) diluted in 5% NDS overnight at 4°C. After washing with PBS, sections were

(19) A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancerNature communicationsDecember 8, 2021Liu Y, Wu Z, Zhou J, Ramadurai DKA, Mortenson KL, Aguilera-Jimenez E, Yan Y, Yang X, Taylor AM, Varley KE, et al.to nitrocellulose membranes. For immunoblotting, we used primary antibodies of SOX2 (Cell Signaling, 3728, rabbit monoclonal, clone C70B1, 1:1000 dilution), ACTIN (Santa Cruz, sc-47778, mouse monoclonal, clone

(20) Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 moduleNature communicationsNovember 12, 2021Harada Y, Yamada M, Imayoshi I, Kageyama R, Suzuki Y, Kuniya T, Furutachi S, Kawaguchi D, Gotoh Y.rat anti-GFP (1:1000, Nacalai Tesque, Cat# GF090R), anti-Sox2 (1:200, Cell Signaling Technology, Cat# 3728), anti-RFP (1:1000, MBL, Cat# PM005), anti-Fabp7 (BLBP, 1:500, Millipore, Cat# ABN14), mouse anti-S100β

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Sox2 (C70B1) Rabbit mAb (IHC Preferred)

Sox2 (C70B1) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Sox2 (C70B1) Rabbit mAb from Cell Signaling Technology

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