p27 Kip1 (D37H1) Rabbit mAb 3688S from Cell Signaling Technology

Product Specs
Itemp27 Kip1 (D37H1) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number3688S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
Targetp27 Kip1
HostRabbit
NCBI Gene AliasesCDKN4, KIP1, MEN1B, MEN4, P27KIP1
ClonalityMonoclonal
NCBI Full Gene Namecyclin dependent kinase inhibitor 1B
Research AreaCell Cycle / Checkpoint Control
IsotypeIgG
CloneD37H1
Molecular Weight27

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) UBA3 reduction sensitizes cancer cells to NAE inhibitorsLife Sci AllianceApril 29, 2026Yu-Ling Miao, Li-Na Zhou, Shan-Shan Song, Xu-Bin Bao, Xia-Juan Huan, Jian Ding, Jin-Xue Heand stored at −20°C. Antibodies against NAE1/APPBP1 (#14321S), Ubc12 (#5641S), Cdt1 (#8064S), p27 (#3688S), pIκBα (ser32/36; #9246S), and LC3A/B (#4108s) were purchased from Cell Signaling Technology. Antibodies

(2) Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in malignant cellsScientific ReportsJanuary 31, 2026Stefania Moccia, Maria Russo, Carmen Cervellera, Giuseppina Crescente, Carmela Spagnuolo, Gian Luigi Russo(cat. # 12741 S) and p62SQSTM1 (cat. # 5114 S), anti pAMPKThr172 (cat. # 2535 S), anti p27kip1 (cat. # 3688) (Cell Signalling Technology, Milan, Italy), anti α-Tubulin was from MERK-Millipore (cat. # T9026) antibodies.

(3) Response gene to complement 32 promotes tumorigenesis by mediating DNA damage repair and inhibits CD8+ T cells infiltration in diffuse large B-cell lymphomaFront ImmunolJuly 16, 2025Xiyuan Zhang, Tiange Lu, Chunlei Shi, Mengfei Ding, Ling Wang, Xinting Hu, Xin WangGoldenbridge, TA-08, 1:2000). Additional markers including c-myc (18583), Cyclin D1 (2922), CDK4 (12790), p27 (3688), p-ATM (5883), p-ATR (2853), p-CHK1 (2348), IRF1(8478), PD-L1(13684), p-H2AX (9718) were all purchased

(4) Structural Identification of Major Molecular Determinants for Phosphotyrosine Recognition in Tyrosine Kinases Reveals Tumour Promoting and Suppressive FunctionsbioRxivJune 13, 2025Nuo Cheng, Luis R. Millán-Barea, Marc Creixell, Alexis R. Barr, Yi Wen Kong, Brian A. Joughin, Cécile K. Lopez, Jette Lengefeld, James Clarke, Chuan Liu, et al.antibodies used for immunostaining in this study are: Phospho-Ser807/811 Rb (CST 8516 1:2000), p27 (CST 3688 1:1000) and Src (CST 2109 1:1000). Automated image analysis of fixed cells All quantitative image

(5) PRPS activity tunes redox homeostasis in Myc-driven lymphomabioRxiv : the preprint server for biologyFebruary 28, 2025MacMillan AC, Karki B, Yang J, Gertz KR, Zumwalde S, Patel JG, Czyzyk-Krzeska MF, Meller J, Cunningham JT.(Cell Signaling #9701), Histone H3 (Abcam #ab176842), p21 (Santa Cruz #sc-6246), p27 (Cell Signaling #3688), Bim (Cell Signaling #2933), p62 (Cell Signaling #39749), TRX2 (Santa Cruz #sc-133201), Catalase (Cell Signaling

(6) Red ginseng prevents niraparib-induced myelosuppression in C57BL/6 mice via inhibiting p53-mediated upregulation of p21 and p27Journal of Natural MedicinesDecember 30, 2024Huiyan Liao, Xiangdan Hu, Shenming Chen, Zhaofeng Fan, Jing Xiao(213-13-2) were supplied by PeproTech Inc. (Suzhou, China). Rabbit monoclonal anti-p53 (2527) and anti-p27 (3688) antibodies were purchased from Cell Signaling Technology (Danvers, MA). Rabbit monoclonal anti-γ-H2AX

(7) Imbalance of redox homeostasis and altered cellular signaling induced by the metal complexes of terpyridineScientific ReportsNovember 6, 2024Katarzyna Malarz, Patryk Ziola, Dawid Zych, Patryk Rurka, Anna Mrozek-Wilczkiewicz(#4688, CST); cyclin A2 (#4656, CST); cyclin B1 (#4138, CST); p21Waf1/Cip1 (#2947, CST); p27Kip1 (#3688, CST); FECH (sc-377377, Santa Cruz Biotechnology); HO-1 (#5853, CST); mitoferrin 1 (26469-1-AP, Proteintech);

(8) Mir221/222 drive synovial hyperplasia and arthritis by targeting cell cycle inhibitors and chromatin remodeling componentseLifeSeptember 5, 2024Roumelioti F, Tzaferis C, Konstantopoulos D, Papadopoulou D, Prados A, Sakkou M, Liakos A, Chouvardas P, Meletakos T, Pandis Y, et al.probed overnight with the following Abs: ACTIN (sc-1615, Santa Cruz Biotechnology, 1:2000), CDKN1B (3688, Cell Signaling, 1:1000), CDKN1C (ab-4058, Abcam, 1/800), and SMARCA1 (ab-172483, Abcam, 1/1000). Relative

(9) Fatty Acid Synthase Promotes Hepatocellular Carcinoma Growth via S-Phase Kinase-Associated Protein 2/p27KIP1 RegulationMedicina (Kaunas)July 18, 2024Antonio Cigliano, Maria M. Simile, Gianpaolo Vidili, Giovanni M. Pes, Maria P. Dore, Francesco Urigo, Eleonora Cossu, Li Che, Claudio Feo, Sara M. Steinmann, et al.anti-FASN (# 3180; Cell Signaling Technology), SKP2 (# ab183039; Abcam, Cambridge, United Kingdom), p27 (# 3688; Cell Signaling Technology), and anti-β-Actin (# ab20272; Abcam). Each primary antibody was followed

(10) Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in miceCell ReportsMarch 26, 2024Pingping Wang, Qianqian Kang, Wen-Shu Wu, Liangyou Ruianti-p21Cip1,Sigma,Cat#MAB88058; RRID:AB_2291542 Rabbit monoclonal anti-p27Kip1,Cell Signaling Technology,Cat#3688; RRID:AB_2077836 Mouse monoclonal anti-p300,Upstate Biotechnology,Cat#05–267; RRID: AB_11213111 Rabbit

(11) 5-methoxytryptophan induced apoptosis and PI3K/Akt/FoxO3a phosphorylation in colorectal cancerWorld Journal of GastroenterologyDecember 21, 2023Tian-Lei Zhao, Yue Qi, Yi-Fan Wang, Yi Wang, Hui Liang, Ya-Bin Puanti-Bim (1:1000, Cell Signaling Technology, #2933), anti-P27 (1:1000, Cell Signaling Technology, #3688) and anti-Cyclin D1 (1:1000, Cell Signaling Technology, #55506). Membranes were washed, incubated with

(12) FoxO3 normalizes Smad3-induced arterial smooth muscle cell growthFrontiers in PhysiologyAugust 24, 2023Jake T. Francisco, Andrew W. Holt, Michael T. Bullock, Madison D. Williams, Cere E. Poovey, Nathan A. Holland, Jeffrey J. Brault, David A. TulisSmurf-2 (#12024; Cell Signaling Technology); p21 Waf1/Cip1 (#2947; Cell Signaling Technology); p27 Kip1 (#3688; Cell Signaling Technology); GAPDH (#2118; Cell Signaling Technology); lamin A/C (#612621; BD Transduction

(13) Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cellsScientific reportsFebruary 10, 2023Kim Y, Yu N, Jang YE, Lee E, Jung Y, Lee DJ, Taylor WR, Jo H, Kim J, Lee S, et al.Atlas antibodies. Anti-p-SMAD1/5/8 (cat. no. 13820T), anti-SMAD1 (cat. no. 9743S), anti-p27 (cat. no. 3688S), and anti-cyclinD1 (cat.no. 2922) antibodies were purchased from Cell Signaling Technology. Anti-BMP-7

(14) Tasquinimod suppresses tumor cell growth and bone resorption by targeting immunosuppressive myeloid cells and inhibiting c-MYC expression in multiple myelomaJournal for immunotherapy of cancerJanuary 1, 2023Fan R, Satilmis H, Vandewalle N, Verheye E, Vlummens P, Maes A, Muylaert C, De Bruyne E, Menu E, Evans H, et al.p-STAT3 (Y705) (#9145), p-STAT3 (S727) (#9138), rabbit-anti STAT3 (#4094), c-MYC (#5605), p27 Kip1(#3688), HDAC4 (#2072), α-TUBULIN (#2144), β-ACTIN (#4907) and horseradish peroxidase (HRP)-coupled anti-rabbit

(15) Identification of a Novel Curcumin Derivative Influencing Notch Pathway and DNA Damage as a Potential Therapeutic Agent in T-ALLCancers (Basel)November 24, 2022Nadezda Zhdanovskaya, Sara Lazzari, Diego Caprioglio, Mariarosaria Firrincieli, Chiara Maioli, Eleonora Pace, Daniela Imperio, Claudio Talora, Diana Bellavia, Saula Checquolo, et al.Notch3 (2889; Cell Signaling Technology), PARP (9542; Cell Signaling Technology), p27 Kip1 (D37H1) (3688; Cell Signaling Technology), pcdc2 Tyr15 (10A11) (4539; Cell Signaling Technology), cdc2 (77055; Cell Signaling Technology

(16) The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signalingThe Journal of biological chemistryNovember 1, 2022Gayen M, Benoit MR, Fan Q, Hudobenko J, Yan R.(Santa Cruz Biotechnology; catalog no.: sc-6246, RRID: AB_628073), p27 (Cell Signaling Technology; catalog no.: 3688, RRID: AB_2077836), Bax (Santa Cruz Biotechnology; catalog no.: sc-493, RRID: AB_2227995), Bim (Cell Signaling Technology

(17) Validation of a non-oncogene encoded vulnerability to exportin 1 inhibition in pediatric renal tumorsMed (N Y)November 1, 2022Diego F. Coutinho, Prabhjot S. Mundi, Lianna J. Marks, Chelsey Burke, Michael V. Ortiz, Daniel Diolaiti, Lauren Bird, Kelly L. Vallance, Glorymar Ibáñez, Daoqi You, et al.antibody; 1:1000,CST,"Cat# 2947, RRID: AB 823586" p27 Kip1 (D37H1) mAb antibody; 1:1000,CST,"Cat# 3688, RRID: AB 2077836" Cleaved PARP (Asp214) (D64E10) antibody; 1:1000,CST,"Cat# 5625, RRID: AB 10699459" c-Myc

(18) SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapyNeoplasia (New York, N.Y.)October 1, 2022Zhou LN, Xiong C, Cheng YJ, Song SS, Bao XB, Huan XJ, Wang TY, Zhang A, Miao ZH, He JX.(#14234S); Ubc9 (#4786S); Cul3 (#2759S); Cul4A (#2699S); NAE1/APPBP1 (#14321S); Cdt1 (#8064S); p27 (#3688S); p-Chk1-Ser317 (#2344S); Chk1 (#2360S); p-Chk2-T68 (#2661S); γH2AX (#2577L); Caspase-8 (#4790S); cleaved

(19) STAT5b is a marker of poor prognosis, rather than a therapeutic target in glioblastomasInternational Journal of OncologySeptember 5, 2022Nadège Dubois, Sharon Berendsen, Katherine Tan, Laurent Schoysmans, Wim Spliet, Tatjana Seute, Vincent Bours, Pierre A. Robe1:10,000 in 4% non-fat dry milk, 1X TBS, 0.1% Tween® 20), p27 (Cell Signaling Technology, Inc.; cat. no. 3688; 1:1,000 in 4% BSA 1X TBS, 0.1% Tween® 20 buffer), Cyclin D1 (Cell Signaling Technology, Inc.; cat.

(20) Inhibition of proteasomal deubiquitinases USP14 and UCHL5 overcomes tyrosine kinase inhibitor resistance in chronic myeloid leukaemiaClinical and translational medicineSeptember 1, 2022Jiang L, He Q, Chen X, Liu A, Ding W, Zhang H, Chen X, Zhou H, Meng Y, Liu B, et al.antibodies as follows were obtained from Cell Signaling Technology (Danvers, MA): PARP (#9532S), p27 (#3688S), USP14 (#11931S), Caspase‐3 (#9662S), Caspase‐8 (#9746S), Caspase‐9 (#9508S), XIAP (#2042S), Bax (#5023),

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p27 Kip1 (D37H1) Rabbit mAb

p27 Kip1 (D37H1) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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p27 Kip1 (D37H1) Rabbit mAb from Cell Signaling Technology

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