p115 RhoGEF (D25D2) XP ® Rabbit mAb 3669S from Cell Signaling Technology

Product Specs
Itemp115 RhoGEF (D25D2) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $371.00 Inquire
Catalog Number3669S
Quantity100 µl
ApplicationsW, IP, IF-IC
ReactivityH, M, R, Mk
TargetARHGEF1
HostRabbit
NCBI Gene AliasesGEF1, IMD62, LBCL2, LSC, P115-RHOGEF, SUB1.5
ClonalityMonoclonal
NCBI Full Gene NameRho guanine nucleotide exchange factor 1
Research AreaCytoskeletal Signaling
CloneD25D2
Molecular Weight115

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Species-Deconvolved Proteomics for In Situ Investigation of Tumor-Stroma Interactions after Treatment of Pancreatic Cancer Patient-Derived Xenografts with Combined Gemcitabine and PaclitaxelJournal of proteome researchJuly 7, 2023Wang X, Niu J, Qian S, Shen S, Straubinger RM, Qu J.antibody overnight at 4 °C. The antibodies were: anti-SDF-2 (sc233291, Abcam, UK), anti-p115 RhoGEF (3669, Cell Signaling Technology, Inc., Danvers, MA), antitropomyosin (sc-74480, Santa Cruz Biotechnology, Inc

(2) Mevastatin promotes healing by targeting caveolin-1 to restore EGFR signalingJCI InsightDecember 5, 2019Andrew P. Sawaya, Ivan Jozic, Rivka C. Stone, Irena Pastar, Andjela N. Egger, Olivera Stojadinovic, George D. Glinos, Robert S. Kirsner, Marjana Tomic-CanicTransduction Laboratories; 610182), anti-ArhGEF1 (D25D2) (rabbit, 1:1000; Cell Signaling Technology; 3669), anti-Rac2 (goat, 1:1000; Abcam; ab2244), and anti–Cyclin B1 (V152) (mouse, 1:1000; Abcam; ab72). For

(3) Wnt5a induces ROR1 to recruit cortactin to promote breast-cancer migration and metastasisnpj Breast CancerDecember 1, 2019Md Kamrul Hasan, George F. Widhopf, Suping Zhang, Sharon M. Lam, Zhouxin Shen, Steven P. Briggs, Barbara A. Parker, Thomas J. Kipps(Y421) (Cell Signaling; dilution 1:500, catalog#4569), ARHGEF1 (Cell Signaling; dilution 1:1000, catalog#3669), β-actin (Cell Signaling; dilution 1:1000, catalog#8457), Src (Cell Signaling; dilution 1:1000, catalog#2109),

(4) Peptide density targets and impedes triple negative breast cancer metastasisNature CommunicationsDecember 1, 2018Daxing Liu, Peng Guo, Craig McCarthy, Biran Wang, Yu Tao, Debra Augustethe specific primary antibodies: antibodies to β-actin (1:5000, 4967S), p115 RhoGEF (D25D2) (1:1000, 3669S), p-PI3K p85(Y458)/p55(Y199) (1:1000, 4228P), PI3 Kinase p85 (1:1000, 4292S) (Cell Signaling Technology),

(5) A RhoA-YAP-c-Myc signaling axis promotes the development of polycystic kidney diseaseGenes & developmentJune 1, 2018Cai J, Song X, Wang W, Watnick T, Pei Y, Qian F, Pan D.Abcam, ab136072), anti-GEF-H1 (1:100; Cell Signaling, 4076), anti-p115RhoGEF (1:100; Cell Signaling, 3669), anti-AKAP13 (1:100; Sigma, SAB140866), anti-p63RhoGEF (1:100; Sigma, SAB2701512), and anti-TRIO (1:100;

(6) Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEFMolecular biology of the cellMay 1, 2016Scott DW, Tolbert CE, Burridge K.5′-UAAGGCUAUGAAGAGAUAC-3′. Antibodies The following antibodies were used for Western blot analysis: anti–GEF-H1 (4076), anti-p115RhoGEF (3669), anti-RhoA (2117), anti–phospho-FAK (3283), anti–phospho-Erk1/2 (4370), phospho-Akt (2965), FAK (3285),

(7) Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferationThe Journal of clinical investigationFebruary 1, 2016Yu J, Chen L, Cui B, Widhopf GF 2nd, Shen Z, Wu R, Zhang L, Zhang S, Briggs SP, Kipps TJ.antibody (sc-374174) was obtained from Santa Cruz Biotechnology; the anti-ARHGEF1 antibody (catalog 3669) was purchased from Cell Signaling Technology; the anti-ARHGEF2 (ab90783) and anti-ARHGEF6 (ab91562)

(8) F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signallingNature communicationsJanuary 27, 2016Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, van Unen J, Pitter B, Huveneers S, Goedhart J, et al.for WB), phosphor-Myosin light-chain Thr18/Ser19 (Cat #3674) (1:100 for IF), p115RhoGEF (D25D2) (Cat #3669) (1:1,000 for WB), RhoA (67B9) (Cat #2117X) (1:1,000 for WB) and CD31 (PECAM-1) (89C2) (Cat #3528) (1:1000

(9) ifn-γ-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injuryCell death & diseaseJuly 4, 2013Ishii H, Tanabe S, Ueno M, Kubo T, Kayama H, Serada S, Fujimoto M, Takeda K, Naka T, Yamashita T.Medicine, Osaka University, 2-2 Yamadaoka, Osaka 565-0871, Japan. Tel: þ 81 66 879 3661; Fax: þ 81 66 879 3669; E-mail: yamashita@molneu.med.osaka-u.ac.jp Keywords: Th1 cells; spinal cord injury; microglia macrophages;

(10) Bilateral movement training promotes axonal remodeling of the corticospinal tract and recovery of motor function following traumatic brain injury in miceCell Death & DiseaseMarch 7, 2013H Nakagawa, M Ueno, T Itokazu, T YamashitaUniversity, 2-2 Yamadaoka, Suita-shi, Osaka 565-0871, Japan. Tel: +81 6 6879 3661; Fax: +81 6 6879 3669; E-mail: yamashita@molneu.med.osaka-u.ac.jp Keywords: traumatic brain injury; rehabilitative training;

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p115 RhoGEF (D25D2) XP ® Rabbit mAb

p115 RhoGEF (D25D2) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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p115 RhoGEF (D25D2) XP ® Rabbit mAb from Cell Signaling Technology

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