DNMT3A (D23G1) Rabbit mAb 3598S from Cell Signaling Technology

Product Specs
ItemDNMT3A (D23G1) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number3598S
Quantity100 µl
ApplicationsW, IP, IHC-P
ReactivityH, M, R, Mk, B
TargetDNMT3A
IsotypeIgG
HostRabbit
NCBI Gene AliasesDNMT3A2, HESJAS, M.HsaIIIA, TBRS
NCBI Full Gene NameDNA methyltransferase 3 alpha
CloneD23G1
Molecular Weight130
ClonalityMonoclonal
Research AreaChromatin Regulation / Nuclear Function

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) VDR-Spermidine Axis Protects Against Age-Related Granulosa Cell Dysfunction and Follicular Decline via DNMTs-Mediated p53 MethylationInt J Biol SciMay 18, 2026Haiyun Chen, Qinghe Geng, Qiuyi Wang, Yuanqin Li, Luxi Shangguan, Zhengquan Zhu, Jingwen Zhang, Shuan Wang, Xiaotian Chen, Shanmei Shen, et al.ab270268, Abcam), Phospho-Histone H2A.X (1:2000, 9718T, CST), DNMT1 (1:1000, 5032T, CST), DNMT3A (1:1000, 3598T, CST), p21 (1:1000, 10355-1-AP, Proteintech), p21 (1:1000, ab188224, Abcam), p53 (1:1500, ab26, Abcam),

(2) Dnmt3a-dependent de novo DNA methylation enforces lineage commitment and preserves functionality of memory Th1 and Tfh cellsCell ReportsMarch 24, 2026Bryant Perkins, Camille L. Novis, Andrew Baessler, Linda M. Sircy, Monyca M. Thomas, Malia Harrison-Chau, Andrew W. Richens, Bryce Fuchs, Nguyen X. Nguyen, Kaitlyn Flint, et al.APC,Invitrogen,catalog # 17-5773-82; clone # FJK-16s; RRID: AB_469457 anti-Dnmt3a,Cell Signaling,catalog # 3598; clone #D23G1; RRID: AB_2277449 Bacterial and virus strains,Bacterial and virus strains,Bacterial and

(3) Polθ activity modulates sensitivity to standard therapies in DNMT3A-deficient leukemiaCell Rep MedMarch 17, 2026Bac Viet Le, Umeshkumar Vekariya, Monika M. Toma, Margaret Nieborowska-Skorska, Marie-Christine Caron, Malgorzata Gozdecka, Zayd Haydar, Martin Walsh, Jayashri Ghosh, Elaine Vaughan-Williams, et al.anti-BrdU,Abcam,Cat#ab6326; RRID: AB_2313786 Rabbit monoclonal anti-DNMT3A,Cell Signaling Technology,Cat#3598; RRID: AB_2277449 Rabbit polyclonal anti-TET2,Cell Signaling Technology,Cat#45010; RRID: AB_2799277 Rabbit

(4) Mouse germline cysts contain a fusome-like structure that mediates oocyte developmenteLifeMarch 11, 2026Madhulika Pathak, Allan C Spradling"Santa Cruz Biotechnology, Inc","sc-271110, RRID:AB_10611939",IF (1:200) Antibody,Dnmt3a,Cell Signaling. Tech,"3598, RRID:AB_2277449",IF (1:200) Antibody,ATP5A,Abcam,"ab14748, RRID:AB_301447",IF (1:200) Sequence-based

(5) Mouse germline cysts contain a fusome-like structure that mediates oocyte developmentElifeMarch 11, 2026Madhulika Pathak, Allan C Spradling"Santa Cruz Biotechnology, Inc","sc-271110, RRID:AB_10611939",IF (1:200) Antibody,Dnmt3a,Cell Signaling. Tech,"3598, RRID:AB_2277449",IF (1:200) Antibody,ATP5A,Abcam,"ab14748, RRID:AB_301447",IF (1:200) Sequence-based

(6) Exosomal miR-29a-3p derived from bone marrow stromal cells suppresses malignant behavior of NSCLC by regulating DNMT3A/JAK2/STAT3 axisOrganogenesisDecember 31, 2025Chao Su, Xiaoliang Han, Kang ZhangCD63 (AF5117, Affinity, Jiangsu, China), CD81 (DF2306, Affinity), Calnexin (AF5362, Affinity), DNMT3A (3598, CST, Shanghai, China), JAK2 (3230, CST), p-JAK2 (3771, CST), STAT3 (4904, CST), p-STAT3 (9145, CST),

(7) MUC1-C auto-regulatory complex with EBNA1 is responsible for latent Epstein-Barr virus-associated gastric cancer progressionOncogeneOctober 7, 2025Hiroki Ozawa, Yin Wang, Henry G. Withers, Naoki Haratake, Ayako Nakashoji, Atrayee Bhattacharya, Atsushi Fushimi, Chie Kikutake, Kazuhiro Yamanoi, Shaowen White, et al.1:1000 dilution; abcam, Cambridge, MA, USA), anti-DNMT1 (5032, 1:1000 dilution; CST), anti-DNMT3A (3598, 1:1000 dilution; CST), anti-DNMT3B (67259, 1:1000 dilution; CST), anti-PLOD1 (29480-1-AP, 1:100 dilution;

(8) Epigenetic modulation of BARD1 to enhance anti-VEGF therapyCell reports. MedicineSeptember 16, 2025Bayraktar E, Rodriguez-Aguayo C, Stur E, Kumar S, Mangala LS, Jennings NB, Bayram NN, Corvigno S, Asare A, Ivan C, et al.RRID:AB_477629 TET1,Thermo Fisher Scientific,Cat# MA5-16312; RRID:AB_2537831 DNMT3A (for WB),Cell Signaling,Cat# 3598; RRID:AB_2277449 DNMT3A (for CHIP),Cell Signaling,Cat# 49768; RRID:AB_2799365 Anti-rabbit secondary

(9) DNA methylation regulates the extinction of fear memoryWorld J PsychiatryJuly 19, 2025Le Jiang, Rui-Xue Ma, Er-Shu He, Xiao-Ye Zheng, Xin Peng, Wen-Hao Ma, Ying Li, Han-Wei Li, Xue-Yan Zhang, Jie-Yu Ji, et al.temperature. The section was incubated with primary antibody [anti-Dnmt3a (Rabbit), 1:500-1:1000, CST, #3598] overnight at room temperature, washed with PBS three times (each for 10 minutes), incubated with secondary

(10) Fumonisin B1 induces global DNA hypermethylation in human glioblastoma U87MG cellsEpigeneticsJune 26, 2025Ashmika Foolchand, Terisha Ghazi, Anil A. Chuturgoon(D63A6) Rabbit mAb,2:1000,Cell Signalling,5032 S DNMT3A (D23G1) Rabbit mAb,2:1000,Cell Signalling,3598 S Anti-MBD2/3 (D-7) Mouse,1:1000,Santa Cruz,"Sc -271,562" Anti-Rabbit IgG HRP,2:5000,Cell Signalling,7074S Anti-mouse

(11) Vagus Nerve Stimulation Inhibits DNA and RNA Methylation in a Rat Model of Pilocarpine-Induced Temporal Lobe EpilepsyCNS Neurosci TherJune 18, 2025Zhonghua Xiong, Jing Zhang, Qinqin Deng, Minghui Wang, Tianfu Lifollowing primary antibodies: anti‐DNMT1(Rabbit D63A6, 1:1000, Cell signaling, Beverly), anti‐DNMT3A(Rabbit 3598S, 1:1000, Cell signaling, Beverly), anti‐METTL3 (Rabbit A8370, 1:1000, ABclonal, Woburn), and anti‐METTL14

(12) DNA hypomethylation modification promotes BST2 expression in cervical cancer by facilitating STAT1 binding to the promoter of BST2Infect Agent CancerJune 13, 2025Reziwanguli Wubuli, Zumurelaiti Ainiwaer, Mayinuer Niyazi, Lili Hananti-DNMT1 (1:1,000; cat. no. sc-514784; Santa Cruz Biotechnology), anti-DNMT3a (1:1,000; cat. no. 3598; Cell Signaling Technology), anti-DNMT3b (1:1,000; cat. no. sc-393845; Santa Cruz Biotechnology), anti-STAT1

(13) Staphylococcus aureus α-hemolysin induces DNA methylation changes in human Th1 cellsImmunol ResJune 11, 2025Iwona Karwaciak, Joanna Pastwińska, Anna Sałkowska, Kaja Karaś, Marta Sobalska-Kwapis, Jarosław Dastych, Marcin Ratajewskipreviously described [21]. The antibodies used included anti-DNMT1 (D63A6) (#5032), anti-DNMT3A (D23G1) (#3598), anti-DNMT3L (E1Y7Q) (#13,451), anti-HELLS (#7998), anti-tri-methyl-histone H3 (Lys36) (D5A7) (#4909),

(14) DNMT3A-dependent DNA methylation shapes the endothelial enhancer landscapeNucleic Acids ResMay 30, 2025Stephanie Gehrs, Zuguang Gu, Joschka Hey, Dieter Weichenhan, Niklas Buckwalter, Moritz Jakab, Agnes Hotz-Wagenblatt, Kersten Breuer, Maria Llamazares Prada, Daniel Hübschmann, et al.primary antibodies (anti-mouse CD31, BD Pharmingen, RRID: AB_396660, 1:100; anti-DNMT3A, Cell Signaling, #3598S, 1:100). After washing with tris-buffered saline with Tween 20 (TBST), the sections were incubated with

(15) GSK-3484862, a DNMT1 degrader, promotes DNMT3B expression in lung cancer cellsNAR CancerMay 27, 2025Qin Chen, Swanand Hardikar, Kimie Kondo, Nan Dai, Ivan R Corrêa Jr, Meigen Yu, Marcos R Estecio, Xing Zhang, Taiping Chen, Xiaodong Chengantibodies were used in this study: DNMT1 [Cell Signaling Technology (CST), Cat. #5032], DNMT3A (CST, Cat. #3598), DNMT3B (CST, Cat. #72335), H3 (CST, Cat. #14269), GAPDH (CST, Cat. #2118), actin (Sigma, Cat. #A2228),

(16) Structure–Activity Relationship Studies of DNA Methyltransferase 1 Monovalent DegradersJournal of Medicinal ChemistryFebruary 13, 2025Chao Qian, Youngeun Lee, Yulin Han, Yue Zhong, Jujun Zhou, Joel Hrit, Ling Xie, Qin Chen, H. Ümit Kaniskan, Xian Chen, et al.were used in the study: DNMT1 (Cell Signaling Technology, 5032), DNMT3A (Cell Signaling Technology, 3598S), DNMT3B (Cell Signaling Technology, 67259S), Nedd4 (Cell Signaling Technology, 2740), Smurf2 (Cell Signaling Technology

(17) Quinoline-based compounds can inhibit diverse enzymes that act on DNACell Chemical BiologyDecember 19, 2024Jujun Zhou, Qin Chen, Ren Ren, Jie Yang, Bigang Liu, John R. Horton, Caleb Chang, Chuxuan Li, Leora Maksoud, Yifei Yang, et al.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies DNMT1,Cell Signaling Technology,Cat#5032 DNMT3A,CST,Cat#3598 Histone H3,CST,Cat#14269 GAPDH,CST,Cat#2118 H2AX,CST,Cat#2595 γH2AX,CST,Cat#9718 HRP-conjugated

(18) Study on the Role of Dnmt3a Expression in the Dentate Gyrus of the Hippocampus in Reward MemoryALPHA PSYCHIATRYOctober 30, 2024Department of Human Anatomy, Dali University School of Medicine, Dali, China, Xiaoye Zheng, Ruixue Ma, Department of Human Anatomy, Dali University School of Medicine, Dali, China, Ershu He, Department of Human Anatomy, Dali University School of Medicine, Dali, China, Xin Peng, Department of Human Anatomy, Dali University School of Medicine, Dali, China, Wenhao Ma, Department of Human Anatomy, Dali University School of Medicine, Dali, China, et al.temperature. The sections were incubated with primary antibodies (anti-Dnmt3a [Rabbit], 1:500~1:1000, CST, #3598; anti-c-fos [Rabbit], 1:1000, Abcam, ab190289) overnight at room temperature, washed with PBS 3 times

(19) L-methionine and the L-type Ca2+ channel agonist BAY K 8644 collaboratively contribute to the reduction of depressive-like behavior in miceFrontiers in Neural CircuitsAugust 29, 2024Ershu He, Ruixue Ma, Shanglan Qu, Xiaoye Zheng, Xin Peng, Jieyu Ji, Wenhao Ma, Xueyan Zhang, Ying Li, Hanwei Li, et al.incubated overnight at room temperature with primary antibodies (anti-Dnmt3a (rabbit), 1:1000, CST, #3598; anti-GFAP (rabbit), 1:500, MCE, #264369). The slices were incubated overnight at room temperature,

(20) Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastomaActa Neuropathologica CommunicationsAugust 7, 2024Foteini Tsiami, Chiara Lago, Noemi Pozza, Federica Piccioni, Xuesong Zhao, Fabienne Lülsberg, David E. Root, Luca Tiberi, Marcel Kool, Jens Schittenhelm, et al.abcam), Dnmt1 (1:100, #5032, Cell Signaling), Dnmt1 (1:200, #MA5-32,547, Thermo Fisher), Dnmt3a (1:100, #3598, Cell Signaling) and Dnmt3b (1:200, #ab2851, abcam). Next day, sections were incubated with horse anti-rabbit

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DNMT3A (D23G1) Rabbit mAb

DNMT3A (D23G1) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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DNMT3A (D23G1) Rabbit mAb from Cell Signaling Technology

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