LATS1 (C66B5) Rabbit mAb 3477S from Cell Signaling Technology

Product Specs
ItemLATS1 (C66B5) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number3477S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, Mk
TargetLATS1
IsotypeIgG
HostRabbit
NCBI Gene AliasesWARTS, wts
NCBI Full Gene Namelarge tumor suppressor kinase 1
CloneC66B5
Molecular Weight140
ClonalityMonoclonal
Research AreaCell Cycle / Checkpoint Control

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) FGF2 alleviates LPS-induced acute lung injury by inhibiting ferritinophagy-mediated ferroptosis in AT2 cells via the Hippo-YAP signaling pathwayFront ImmunolApril 17, 2026Yan Wang, Pingjun Zhu, Yongkai Ding, Xinjie Han, Xi Wang, Sheng Wu, Siyuan Huai, Nan Li, Guogang Xu, Yingzhen Du12741), NCOA4 (1:1000, CST, 53234), ferritin heavy chain 1 (FTH1, 1:1000, CST, 3998), LATS1 (1:1000, CST, 3477), MST1 (1:1000, CST, 3682), YAP (1:1000, CST, 14074), phosphorylated YAP (p-YAP, 1:1000, CST, 13008),

(2) Hippo signaling differentially regulates distal progenitor subpopulations and their transitional states to construct the mammalian lungsNature CommunicationsApril 3, 2026Kuan Zhang, Madhuri Basak, Youssef Zaher, Erica Yao, Shao-An Wang, Thin Aung, Pao-Tien ChuangR&D Systems, Cat# AF1042; RRID:AB_2162633), rabbit anti-LATS1 (C66B5) (1:100, Cell Signaling Technology, Cat# 3477S; RRID:AB_2133513), rabbit anti-Phospho-YAP (Ser127) (1:100, Cell Signaling Technology, Cat# 4911S; RRID:AB_2218913),

(3) Mesenchymal stem cells differentiate dynamic from static load through variable regulation of the Hippo pathwayJournal of BiomechanicsApril 1, 2026Zhihui Xie, Buer Sen, Nina Nikitina, Sean Howard, Maya Styner, Clinton Rubin, Gunes Uzer, Janet RubinPhospho-YAP-ser127 (cat# 13008S, Cell Signaling), PP2A-Cα/β (cat# sc-80665, Santa Cruz), LATS1 (cat# 3477S, Cell Signaling), Phospho-LATS1 (Ser909) (cat# 9157S, Cell Signaling), MST1 (D8B9Q) (cat#14946S, Cell Signaling

(4) Piperlongumine suppresses YAP-ET-1-CXCL2 signaling to modulates aggressiveness of triple-negative breast cancer cellsTranslational OncologyApril 1, 2026Ming-Yi Hsieh, Ching-Chieh Yang, Wen-Jing Hsu, Zei-Wei Liu, Hsin-Ying Lu, Ming-Chen Chiang, Cheng-Jui Huang, Ching-Yun Liao, Cheng-Wei Lin, Pei-Wei Shueng(#13008), p-YAP (S61) (#75784), p-AMPK (AMPK; #130429), AMPK (#103487), p-LATS1 (S909) (#9157), and LATS1 (#3477) were purchased from Cell Signaling Technology. The antibody for Twist1 (A3237) was purchased from Abclonal.

(5) The WNK-OXSR1 osmosensing pathway mediates intestinal regeneration via Hippo-YAP signalingThe EMBO JournalMarch 18, 2026Heming Cao, Xiawei Huang, Xiaobing Jiang, Jingrong Deng, Jiahui Wang, Chengfang Wu, Minhuang Hu, Bei Zeng, Zhihao Hu, Huimin Pan, et al.(CST #13008, 1:1000), rabbit anti-phospho-YAP (S381) (CST #13619, 1:1000), rabbit anti-LATS1 (CST #3477, 1:1000), rabbit anti-Phospho-LATS1 (T1079) (CST #8654, 1:1000), mouse anti-GAPDH (Abclonal #A19056,

(6) TROP2 confers resistance to oxidative stress-induced cancer cell death through YAP/HMOX1 signalingJ Transl MedMarch 11, 2026Di Wu, Yibing Liu, Ting Zhu, Haisen Zhao, Wanqiao Cao, Xiu Guo, Hongwei Xia, Yonglei Liu#AG2181, Beyotime), YAP1 (1:1000, cat #14074, CST), P-YAP1 (1:1000, cat #13619, CST), LATS1 (1:1000, cat #3477, CST), p-LATS1 (1:1000, cat #9157, CST), Histone3 (1:1000, cat #9715, CST),α-Tubulin (1:1000, cat #2144,

(7) Bushen Huoxue Recipe enhances the immune microenvironment at the maternal-fetal interface via the Hippo signaling pathway in mice with recurrent spontaneous abortionJournal of Traditional and Complementary MedicineMarch 1, 2026Lei Xia, Siqing Huang, Hongli Huang, Xue Han, Li Dong, Yanqiu Xia(Cambridge, MA, USA); Alexa Fluor 555 nm (8953) and antibodies against MST (14946), p-MST (49332), LATS (3477S), p-LATS (8654S), YAP (14074S), p-YAP (13008S), TAZ (83669S), and p-TAZ (59971S) were purchased from

(8) PKC-eta promotes breast cancer metastasis by regulating the Hippo–YAP signaling pathwaySignal Transduction and Targeted TherapyFebruary 17, 2026Vijayasteltar B. Liju, Kamran Waidha, Amitha Muraleedharan, Divya Ram Jayaram, Hodaya Haimov, Sankar Jagadeeshan, Dinesh Babu Manikandan, Raghda Abu Shareb, Livingstone Nurukurti, Menachem Sklarz, et al.used in this study were against YAP (CST, #14074), MST1 (CST, #3682), pMST1 (CST, #3681), LATS1 (CST, #3477), 14-3-3 ζ/δ (CST, #7413), pLATS1 (CST, #8654), pYAP (Ser127) (CST, #13008), pYAP (Ser109) (CST, #53749),

(9) A human patient-derived organoid biobank to model tumor heterogeneity and therapeutic vulnerability for oral squamous cell carcinomaCell Reports MedicineFebruary 17, 2026Yuhan Wang, Pengfei Diao, Pin Lv, Na Qi, Ziyu Wang, Enshi Yan, Jin Li, Yanling Wang, Dongmiao Wang, Yaping Wu, et al.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, Anti-P-LATS1/2,MedChemExpress,Cat#HY-P81210; RRID: AB_3103276 Anti-LATS,Cell Signaling Technology,Cat#3477; RRID: AB_2133513 Anti-P-YAP,Cell Signaling Technology,Cat#13008;RRID: AB_2650553 Anti-YAP,Cell Signaling Technology

(10) HCV infection induces ubiquitin-dependent degradation of LATS1, inactivating the Hippo pathway and upregulating transcription of the CYR61 and CTGF genesJ Gen VirolFebruary 5, 2026Maria Alethea Septianastiti, Chieko Matsui, Zihan Xu, Fransisca Puspitasari, Dewa Nyoman Murti Adyaksa, Lin Deng, Takayuki Abe, Ikuo Shoji(sc-101199; Santa Cruz Biotechnology). The rabbit mAb used in this study was anti-LATS1 (C66B5) mAb (3477; Cell Signaling Technology). The rabbit polyclonal antibodies (pAbs) used in this study included anti-HA

(11) Regulation of tension-dependent localization of LATS1 and LATS2 to adherens junctionsPLoS OneFebruary 2, 2026Chamika De Silva, Brian A. Kelch, Dannel McCollum(TBST) and incubated overnight at 4°C with primary antibodies (rabbit anti-LATS1 (1:500, Cell Signaling, 3477S), rabbit anti-LATS2 (1:500, Cell Signaling, 5888S), rabbit anti-LIMD1 (1:500, Novus biologicals, NBP2–56448),

(12) Heat stress-induced heat shock protein 90 alpha family class A member 1 upregulation stabilizes yes-associated protein through ubiquitination inhibition to boost hepatic cancer radiofrequency hyperthermia resistanceCell Stress and ChaperonesFebruary 1, 2026Zhehan Bao, Yi Jiang, WeiRen Liang, Dinghu Zhang, Liwen GuoName,Brand,Number,Dilution rate β-actin,CST,4970,1:1000 TAZ,CST,8418S,1:1000 LATS1,CST,3477,1:1000 P-LATS1,Proteintech,28998-1-AP,"1:10,000" YAP,CST,14074T,1:1000 p-YAP,CST,13008T,1:1000 HSP110,Proteintech,13383-1-AP,1:1000 HSP90,Proteintech,13171-1-AP,1:2000 HSP70,CST,4873,1:1000 HSP60,Proteintech,15282-1-AP,1:2000 Details

(13) Clostridioides difficile TcdB induces expression of its receptor (CSPG4) through a noncanonical Hippo signaling mechanismJournal of Biological ChemistryFebruary 1, 2026Jason L. Larabee, Elizabeth J. Donald, Anushka A. Sukhadia, Tyler M. Shadid, Sarah J. Miller, Jimmy D. Ballard(Cell Signaling Technology; product # 3418); a rabbit monoclonal against LATS1 (Cell Signaling Technology; product #3477) a rabbit monoclonal against phosphorylated LATS1 (Thr1079) (Cell Signaling Technology; product #8654);

(14) Dose-dependent activation of the Hippo pathway by Type I and Type III interferons suppresses tissue repair by human bronchial epithelial cellsPLOS BiologyJanuary 26, 2026Krupakar V. Subramaniam, Hui Jing Lim, Bao Wang, Valia T. Mihaylova, Evrett N. Thompson, Diane S. Krause, Ellen F. Foxman#13619, 1:1,000), phospho-LATS1 Ser909 (Cell Signaling, #9157, 1:1,000), LATS1 (C66B5, Cell Signaling, #3477, 1:1,000), LATS2 (D83D6, Cell Signaling, #5888, 1:1,000), phospho-MST1 Thr183/MST2 Thr180 (Cell Signaling,

(15) cis-Clerodane-type diterpenoids from Tinospora crispa and their anticancer potentialArchives of Pharmacal ResearchJanuary 20, 2026Se Yun Jeong, Jisun Kim, Ji Won Ha, Norhayati Ahmad, Nurul Hazlina Zaini, Yoon-Joo Ko, Alan Jung Park, Wonhwa Lee, Ki Hyun Kim#13301S, Cell Signaling Technology), MOB1 (1:1000, #13730S, Cell Signaling Technology), LATS1 (1:1000, #3477S, Cell Signaling Technology), phospho-YAP (p-YAP; 1:1000, #4911S, Cell Signaling Technology), YAP (1:1000,

(16) O-GlcNAcylation of the tumor suppressor LATS1 drives mitotic progression via PLK1Journal of Biological ChemistryJanuary 1, 2026Li Meng, Yunfeng Wang, Wen Zhou, Shian Wu, Jing LiA00865), anti-HA (DIA-An, # 3063), anti-OGT (Abcam, # ab96718), anti-LATS1 (Cell Signaling Technology, # 3477S), anti-PLK1 (Santa Cruz Biotechnology, # SC-17783), anti-H3-pS10 (Bethyl, #A301-844A), anti-H3 (Abcam,

(17) FAM189A2 activates Hippo signaling pathway by abrogating WWP2-mediated LATS1 ubiquitination, to inhibit the glycolysis and proliferation processes of lung adenocarcinomaJournal of Translational MedicineDecember 5, 2025Bingyu Chen, Xuezhu Rong, Yuheng Feng, Yuekang Hou, Lin Fu, Qiang Han, Yan Song, Xuyong Linnumber,Concentration FAM189A2,"25630-1-AP, Proteintech",IB/1:500 WWP2,"12197-1-AP, Proteintech",IB/1:1000 LATS1,"3477, Cell Signaling Technology",IB/1:1000 YAP1,"14,074, Cell Signaling Technology",IB/1:1000 p-YAP(S127),"AF3328,

(18) KSR1 is a scaffold for the Hippo signaling pathwayCommun BiolDecember 1, 2025Samar Sayedyahossein, Mohammed Rizwan Babu Sait, Zhigang Li, Riddhi Banerjee, Andy Tran, Louise Thines, Mehdi Karimi, Mehrnoosh Bahmani, Naomi Mishan, Pooya Borzou, et al.1/1000 KSR1,"Abcam, # (ab68483), EPR2421Y, #1001675-13",WB:1/1000 LATS1,"Cell Signaling Technology, #3477, C66B5, #9",IP: 1/50WB:1/1000 LATS1,"Invitrogen, #711149, 2HCLC, #SB246686",IF:1/200 p44/42 MAPK (ERK1/2),"Cell Signaling Technology

(19) Quercetin alleviates rifampicin-induced hepatocyte injury by modulating the Hippo-YAP signaling pathwayFrontiers in MedicineNovember 18, 2025Weiwei Liu, Hui Li, Weimin Luprimary antibodies against Phospho-YAP (Ser127) (#13008, CST, 1:1000), YAP (#4912, CST, 1:1000), LATS1 (#3477, CST, 1:1000), MST1 (#3682, CST, 1:1000), Caspase-3 (#ab32351, Abcam, 1:1000; recognizes both the pro-form

(20) An Inhibitor of Death-Associated Protein Kinase 3 (DAPK3) Disrupts Hippo Signaling and Intestinal Epithelial Regeneration in Murine DSS-Induced ColitisDigestive Diseases and SciencesNovember 7, 2025Huey-Miin Chen, David A. Carlson, Timothy A. J. Haystead, Justin A. MacDonaldphospho[Thr35]-MOB1 (D2F10) rabbit mAb (#8699), MOB1 (E1N9D) rabbit mAb (#13730), LATS1 (C66B5) rabbit mAb, (#3477), GAPDH (14C10) rabbit mAb (#2118), Ki-67 (D3B5) rabbit mAb (#12202), MST1 rabbit IgG (#3682) and MST2

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LATS1 (C66B5) Rabbit mAb

LATS1 (C66B5) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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LATS1 (C66B5) Rabbit mAb from Cell Signaling Technology

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