eIF3A (D51F4) XP ® Rabbit mAb 3411S from Cell Signaling Technology

Product Specs
ItemeIF3A (D51F4) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $371.00 Inquire
Catalog Number3411S
Quantity100 µl
ApplicationsW, IP, IHC-P, IF-IC
ReactivityH, M, R, Mk
TargeteIF3a
HostRabbit
NCBI Gene AliasesEIF3, EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185
ClonalityMonoclonal
NCBI Full Gene Nameeukaryotic translation initiation factor 3 subunit A
Research AreaTranslational Control
IsotypeIgG
CloneD51F4
Molecular Weight166

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) SLC25A5 Suppresses Colorectal Cancer Growth and Metastasis Through Regulation of the EIF3A/PI3K/AKT AxisInt J Mol SciMay 13, 2026Ke Ying, Xiang Zhao, Zhuo Wu, Chi Huang, Qian Wu, Zhongchen Liu(1:100; Abclonal, Woburn, MA, USA, A23411), EIF3A (1:400; Cell Signaling Technology, Danvers, MA, USA, 3411), E-cadherin (1:1600; Cell Signaling Technology, 9782), or N-cadherin (1:400; Cell Signaling Technology,

(2) Distinct modes of non-canonical initiation regulate selective host versus viral mRNA translation during poxvirus-induced shutoffNature MicrobiologyMay 28, 2025Chorong Park, Aaron J. Ferrell, Nathan Meade, Peter S. Shen, Derek Walsh#9165T), MT-CO2 (proteintech, #55070-1-AP), GAPDH (Santa Cruz, sc-365062), eIF3a (Cell Signaling, #3411), eIF3d (Proteintech, 10219-1AP), E3 (From Dr. Jingxin Cao), I3 (From Dr. David Evans), A14 (From Dr.

(3) Ribosome customization and functional diversification among P-stalk proteins regulate late poxvirus protein synthesisCell ReportsJanuary 28, 2025Natalia Khalatyan, Daphne Cornish, Aaron J. Ferrell, Jeffrey N. Savas, Peter S. Shen, Judd F. Hultquist, Derek Walshanti-α-Tubulin,Millipore Sigma,"Cat# T6199, RRID:AB_477583" Rabbit anti-eIF3a,Cell Signaling Technology,"Cat# 3411, RRID:AB_2096523" Mouse anti-ICP0,Abcam,"Cat# ab6513, RRID: AB_305536" Mouse anti-ICP5,Virusys Corporation,"Cat#

(4) Viral PIC-pocketing: RSV sequestration of translational preinitiation complexes into bi-phasic biomolecular condensatesJournal of VirologyMarch 19, 2024Fatoumatta Jobe, James T. Kelly, Jennifer Simpson, Joanna Wells, Stuart D. Armstrong, Matt Spick, Emily Lacey, Leanne Logan, Nophar Geifman, Philippa Hawes, et al.from Affinity Biosciences. Rabbit anti-RPS6 (2217), anti-eIF4G (2467), anti-eIF4E (2067), anti-eIF3A (3411), anti-eIF4A (2013), anti-eIF4A1 (2490), anti-eIF4B (3592), anti-eIF4H (3469), and anti-GAPDH (5174)

(5) METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signalingCell death & diseaseJuly 12, 2023Yin J, Ding F, Cheng Z, Ge X, Li Y, Zeng A, Zhang J, Yan W, Shi Z, Qian X, et al.(71283, CST); YTHDF1 (43123, CST); YTHDF3 (24206, CST); YTHDC1 (81504, CST); YTHDC2 (46324, CST); EIF3 (3411, CST); hnRNPA2B1 (9304, CST); β-catenin (8480, CST); Flag (SAB4301135, Sigma); c-Src (2109, CST); β-catenin

(6) ADAR1 downregulation by autophagy drives senescence independently of RNA editing by enhancing p16(INK4a) levelsNature cell biologyAugust 1, 2022Hao X, Shiromoto Y, Sakurai M, Towers M, Zhang Q, Wu S, Havas A, Wang L, Berger S, Adams PD, et al.anti-ADAR1 (Sigma, cat. no. HPA003890; 1:40) and rabbit anti-EIF3a (Cell Signaling Technology, cat. no. 3411; 1:100). Antibody array analysis The antibody array for secreted factors was performed using a Human

(7) An eIF3d-dependent switch regulates HCMV replication by remodeling the infected cell translation landscape to mimic chronic ER stressCell reportsMay 3, 2022Thompson L, Depledge DP, Burgess HM, Mohr I.REAGENT or RESOURCE,SOURCE,IDENTIFIER Antibodies,, anti-eIF3a,Cell Signaling,cat# 3411S anti-eIF3b,Bethyl,cat# A301-761A anti-eIF3d,Proteintech,cat# 10219-1-AP anti-eIF3e,Bethyl,cat# A302-985A anti-eIF3g,Bethyl,cat#

(8) The METTL5-TRMT112 N(6)-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylationThe Journal of biological chemistryMarch 1, 2022Sepich-Poore C, Zheng Z, Schmitt E, Wen K, Zhang ZS, Cui XL, Dai Q, Zhu AC, Zhang L, Sanchez Castillo A, et al.dilution anti-RPS6,Abcam/70227,Western blot/rabbit/1:1000 dilution anti-EIF3A,Cell Signaling Technology/3411,Western blot/rabbit/1:1000 dilution anti-EIF4E,Cell Signaling Technology/2067,Western blot/rabbit/1:1000

(9) Early motor outcomes in infants with critical congenital heart disease are related to neonatal brain development and brain injuryDevelopmental Medicine & Child NeurologyFebruary 1, 2022Raymond Stegeman, Maaike C A Sprong, Johannes M P J Breur, Floris Groenendaal, Linda S de Vries, Felix Haas, Janjaap van der Net, Nicolaas J G Jansen, Manon J N L Benders, Nathalie H P Claessens, et al.Characteristic,n=51 "Male, n (%)",31 (61) "Gestational age, wks",39.6±1.4 "Birthweight, g",3411±594 "Prenatal diagnosis, n (%)",37 (73) "Congenital heart disease, n (%)","Congenital heart disease

(10) METTL16 exerts an m(6)A-independent function to facilitate translation and tumorigenesisNature cell biologyFebruary 1, 2022Su R, Dong L, Li Y, Gao M, He PC, Liu W, Wei J, Zhao Z, Gao L, Han L, et al.(Thermo Fisher Scientific). 2–8 μg anti-FLAG antibody (F3165, Sigma-Aldrich), anti-eIF3a antibody (3411S, Cell Signaling Technology), anti-eIF3b (1:1000, sc-137214, Santa Cruz Biotechnology), and IgG (12–371,

(11) Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stressNature chemical biologyFebruary 1, 2022Shu XE, Mao Y, Jia L, Qian SB.time points. 4-Hydroxytamoxifen (H7904) and Thiamet G (SML0244) were purchased from Sigma. Anti-eIF3A (3411), anti-RPS6 (2217), anti-p-eIF2α Ser51 (3398), anti-eIF2α (9722), anti-MMK6/MAP2K6 (9264), anti-eIF3C

(12) Bi-directional ribosome scanning controls the stringency of start codon selectionNature CommunicationsDecember 1, 2021Yifei Gu, Yuanhui Mao, Longfei Jia, Leiming Dong, Shu-Bing Qiantogether and mixed thoroughly to get 600 μl total sample. 5 μg/mg lysate eIF3a antibody (Cell signaling 3411 S) and 0.5 U/ μl SUPERase•In (Invitrogen AM2696) were added to the IP samples, followed by incubation

(13) Sugar phosphate activation of the stress sensor eIF2BNature communicationsJune 8, 2021Hao Q, Heo JM, Nocek BP, Hicks KG, Stoll VS, Remarcik C, Hackett S, LeBon L, Jain R, Eaton D, et al.eIF2Bδ (Proteintech #11332–1-AP); eIF2Bε (Bethyl Labs #A302-556); eIF3a (Cell Signaling Technology #3411); eIF2α (Cell Signaling #5324); p-eIF2α (Cell Signaling #3398); FLAG (Sigma #F1804). All antibodies

(14) Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage responseNucleic acids researchJune 4, 2021Yu F, Wei J, Cui X, Yu C, Ni W, Bungert J, Wu L, He C, Qian Z.(CST#4777S), anti-HA (CST#2362), anti-Flag (Sigma#F1804), anti-IGF2BP2 (CST#14672S), anti-eIF3A (CST#3411S). Drug treatment For the ROS-induced DNA damage analysis, the indicated cell lines were treated with

(15) Thiopurines activate an antiviral unfolded protein response that blocks influenza A virus glycoprotein accumulationJournal of virologyMay 10, 2021Slaine PD, Kleer M, Duguay BA, Pringle ES, Kadijk E, Ying S, Balgi A, Roberge M, McCormick C, Khaperskyy DA.10E10; Santa Cruz), rabbit anti-TIAR (catalog number 8509; Santa Cruz), and anti-eIF3A (catalog number 3411; Cell Signaling), followed by Alexa-coupled donkey secondary antibodies (Thermo Fisher Scientific) at

(16) Interactome Mapping of eIF3A in a Colon Cancer and an Immortalized Embryonic Cell Line Using Proximity-Dependent Biotin IdentificationCancersMarch 14, 2021Vo DK, Engler A, Stoimenovski D, Hartig R, Kaehne T, Kalinski T, Naumann M, Haybaeck J, Nass N.essentially as described previously [41]. The following additional antibodies were used: eIF3A (Cat# 3411), Cell Signaling (Danvers, MA, USA); β-actin (Cat# A5441, Sigma-Aldrich (Steinheim, Germany). Detection

(17) G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signalingCellFebruary 4, 2021Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, et al.RRID: AB_2230924 EIF2S1-pS51,Cell Signaling,Cat# 9721; RRID: AB_330951 EIF3A,Cell Signaling,Cat# 3411; RRID: AB_2096523 FLAG,Sigma-Aldrich,Cat# F3165; RRID: AB_259529 G3BP1,Santa Cruz,Cat# sc-365338;

(18) N6-methyladenosine regulates ATM expression and downstream signalingJournal of CancerJanuary 1, 2021Zhang X, Liu P, Zheng X, Wang J, Peng Q, Li Z, Wei L, Liu C, Wu Y, Wen Y, et al.Proteintech); H2A.X (A11361, ABclonal); γH2A.X (AP0687, ABclonal ); GAPDH(60004-1-Ig, Proteintech); eIF3A (3411T, CST); Flag (F1804, Sigma-Aldrich); anti‐rabbit IgG HRP‐linked antibody (7074; CST); Peroxidase-conjugated

(19) UV damage induces G3BP1-dependent stress granule formation that is not driven by mTOR inhibition-mediated translation arrestJournal of cell scienceOctober 28, 2020Ying S, Khaperskyy DA.Santa Cruz Biotechnology, sc-47778); eIF2α (1:1000; rabbit, Cell Signaling, #5324); eIF3A (1:1000; rabbit, Cell Signaling, #3411); eIF3B (1:2000; rabbit, Bethyl Labs., A301-761A); eIF4E (1:1000; rabbit, Cell Signaling, #2067); eIF4G

(20) EIF3H promotes aggressiveness of esophageal squamous cell carcinoma by modulating Snail stabilityJournal of experimental & clinical cancer research : CRAugust 31, 2020Guo X, Zhu R, Luo A, Zhou H, Ding F, Yang H, Liu Z.Ubiquitin (#3936, CST), Vimentin (#5741, CST), N-cadherin (#13116, CST), E-cadherin (#3195, CST), EIF3A (#3411, CST), EIF3I (#ab40745, Abcam) were used. Normal rabbit IgG (#2729, CST), anti-c-MYC agarose affinity

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eIF3A (D51F4) XP ® Rabbit mAb

eIF3A (D51F4) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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eIF3A (D51F4) XP ® Rabbit mAb from Cell Signaling Technology

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