The Rabbit Anti-Metalloproteinase inhibitor 1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TIMP1. This antibody recognizes Rat antigen. The Rabbit Anti-Metalloproteinase inhibitor 1 Antibody has been shown to work in the following applications: EIA, Immunoassay, and ELISA.
Description
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells; procathepsin L is required for maximal activity