The Anti-Mitochondrial Pyruvate dehydrogenase kinase 1 antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PDK1, PDPK1, and pyruvate dehydrogenase kinase 1. This antibody recognizes Human, and Rat antigen. The Anti-Mitochondrial Pyruvate dehydrogenase kinase 1 antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Description: Rabbit IgG polyclonal antibody for[Pyruvate dehydrogenase[lipoamide]] kinase isozyme 1, mitochondrial(PDK1) detection. Tested with WB, IHC-P in Human, Rat.
Background: PDK1(Pyruvate Dehydrogenase Kinase Isoenzyme 1), is an enzyme that in humans is encoded by the PDK1 gene. To find human PDKs, Gudi et al.(1995) used oligonucleotide primers to screen a human liver cDNA library by PCR. They identified and reported the deduced amino acid sequences of PDK1, PDK2, and PDK3. The human PDK1 gene encodes a protein with a predicted molecular mass of 49,244 Da that shares 93% identity with that of the rat PDK1 gene. Northern blot analysis showed that the PDK1 message was expressed predominantly in the heart