The Glial Fibrillary Acidic Protein (GFAP), Polyclonal Antiserum, Rabbit Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GFAP, and Glial Fibrillary Acidic Protein. This antibody recognizes Human, Mouse, Rat, and Feline antigen. The Glial Fibrillary Acidic Protein (GFAP), Polyclonal Antiserum, Rabbit Antibody has been shown to work in the following applications: Immunocytochemistry, Immunohistochemistry, and Western Blot.
Description
Description: Human GFAP is a 49,749 dalton protein (432 amino acids) expressed in astrocytes. GFAP is an intermediate filament protein and acts as an intracellular structural component of the cytoskeleton. During embryonic and fetal life, GFAP is also expressed by radial glial cells of the CNS. Various mutations of the GFAP gene in humans produce Alexander's disease, one of the leukodystrophies. Antibodies to GFAP are therefore very useful as markers of astrocytic cells and neural stem cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP