MyBioSource.com's PSMC3IP antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The PSMC3IP antibody was generated using Hop2 as the antigen and it reacts with Human, Mouse, Rat, Bovine, and Canine.
Description
Rabbit polyclonal PSMC3IP antibody
PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3