The CaVbeta2 Antibody: RPE from MyBioSource.com is a Mouse Monoclonal antibody to CACNB2, and CAVB2. This antibody recognizes Human, Mouse, and Rat antigen. The CaVbeta2 Antibody: RPE has been shown to work in the following applications: Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Background Info: Detects ~78 kDa. No cross reactivity against Cavbeta1, Cavbeta3, Cavbeta4
Scientific Background: Cav Beat subunits are involved in the transport of the pore forming alpha1 subunit to the plasma membrane (3). They also shield an ER Retention signal on the alpha1 subunit, thereby guiding the pore-forming subunit to the target membrane (4, 5). They also determine the biophysical properties of the calcium channel (5)