The Anti-VE Cadherin antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Cadherin 5, CD144, CDH5, VE-Cadherin, Vec, and VEcad. This antibody recognizes Human, Mouse, and Rat antigen. The Anti-VE Cadherin antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Description: Rabbit IgG polyclonal antibody for Cadherin-5(CDH5) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: CDH5(Cadherin 5), also known as VE-cadherin, is a type of cadherin. It is encoded by the human gene CDH5. Kremmidiotis et al.(1998) mapped the human CDH5 gene to 16q22.1 using somatic cell hybrid panels. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Therefore it was concluded that VE-cadherin serves the purpose of maintaining newly formed vessels