Human IL-11 R alpha Antibody MAB1977 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman IL-11 R alpha Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberMAB1977
NCBI Gene AliasesCRSDA
Clone473143
ReactivityHuman,Mouse
IsotypeIgG1
TargetIL-11 R alpha
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
HostMouse
ApplicationsELISA Development,Western Blot
NCBI Full Gene Nameinterleukin 11 receptor subunit alpha
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenMouse myeloma cell line NS0-derived recombinant human IL-11 R alpha, Cys26-Val363, Accession # Q14626
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) IL-11 is a crucial determinant of cardiovascular fibrosisNatureDecember 7, 2017Schafer S, Viswanathan S, Widjaja AA, Lim WW, Moreno-Moral A, DeLaughter DM, Ng B, Patone G, Chow K, Khin E, et al.IgG type 2a (MAB003, R&D Systems), anti-IL-11 antibody (MAB218, R&D Systems), anti- IL11RA antibody (MAB1977, R&D Systems), brefeldin A (B7651, Sigma-Aldrich), cycloheximide (C1988, Sigma-Aldrich), PD98059 (9900,

(2) Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneityNatureOctober 2, 2014Marusyk A, Tabassum DP, Altrock PM, Almendro V, Michor F, Polyak K.Billerica, USA). The following antibodies were used: β-actin (Sigma, # A2228), IL11Rα (R&D systems #MAB1977), HRP conjugated anti-mouse and anti-rabbit (Thermo Scientific). shRNA experiments shRNA constructs

(3) Bovine lactoferricin-induced anti-inflammation is, in part, via up-regulation of interleukin-11 by secondary activation of STAT3 in human articular cartilageThe Journal of biological chemistryNovember 1, 2013Yan D, Kc R, Chen D, Xiao G, Im HJ.

(4) Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teethAmerican journal of human geneticsJuly 15, 2011Nieminen P, Morgan NV, Fenwick AL, Parmanen S, Veistinen L, Mikkola ML, van der Spek PJ, Giraud A, Judd L, Arte S, et al.

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Human IL-11 R alpha Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Human IL-11 R alpha Antibody from R&D Systems, a Bio-Techne Brand

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