The Myogenin Antibody from MyBioSource.com is a Mouse Monoclonal antibody to MYF4, Myog, and myogenin. This antibody recognizes Human, Mouse, and Rat antigen. The Myogenin Antibody has been shown to work in the following applications: ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, Super Shift Assay, and Western Blot.
Description
Recognizes a protein of 34kDa, identified as myogenin. Its epitope localizes between aa 158-178 of myogenin. Myogenin is a member of a family of myogenic regulatory genes, which includes MyoD, myf5 and MRF4. These genes encode a set of transcription factors, which are essential for muscle development. Expression of myogenin is restricted to cells of skeletal muscle origin. It is therefore a useful marker for tumors of the muscle lineage, being strongly expressed in alveolar rhabdomyosarcomas. This antibody can immunoprecipitate protein-DNA complex and is the antibody of choice for staining of formalin-fixed, paraffin-embedded tissues