MyBioSource.com's Anti-HIF3 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Anti-HIF3 antibody was generated using HIF3 alpha, and HIF3A as the antigen and it reacts with Human, and Rat.
Description
Description: Rabbit IgG polyclonal antibody for Hypoxia-inducible factor 3-alpha(HIF3A) detection. Tested with WB in Human, Rat.
Background: Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. HIF3A is mapped to 19q13.32. This gene involved in adaptive response to hypoxia. HIF3A suppresses hypoxia-inducible expression of HIF1A and EPAS1. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element(HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea