The NHE3 Antibody: RPE from MyBioSource.com is a Rabbit Polyclonal antibody to NHE3, and SLC9A3. This antibody recognizes Mouse, and Rat antigen. The NHE3 Antibody: RPE has been shown to work in the following applications: Immunocytochemistry, and Western Blot.
Description
Background Info: Detects ~84kDa
Scientific Background: Sodium-hydrogen exchanger 3 (NHE3; Slc9a3) is an epithelial transport protein that carries out 1:1 exchange of Na+ and H+ across the plasma membrane. It is apically located in the proximal tubule of the kidney, the thick ascending limb of the kidney, and in small intestine (1). NHE3 is phosphorylated and regulated by multiple kinases including PKA, SGK1 and CK2. It can be phosphorylated by calyculin A, and dephosphorylated by PP1 catalytic subunit in vitro (2)