MyBioSource.com's bcl-2 Antibody is a Sheep Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, Immunoprecipitation, and Western Blot. The bcl-2 Antibody was generated using BCL2 as the antigen and it reacts with Human, Rat, and Canine.
Description
Human hematopoetic malignancies are often characterized by gene rearrangements that deregulate gene expression. Antibodies to human bcl-2 (B cell leukemia/lymphoma 2) are directed against the gene isolated at the chromosomal breakpoint t(14;18) Bcl-2 which suppress programmed cell death (apoptosis) and appears to be modulated by association with bax, a cell death promoter