MyBioSource.com's Anti-human CEACAM5 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot. The Anti-human CEACAM5 antibody was generated using CD66e, and CEACAM5 as the antigen and it reacts with Human.
Description
Description: Rabbit IgG polyclonal antibody for Carcinoembryonic antigen-related cell adhesion molecule 5(CEACAM5) detection. Tested with WB, IHC-P, ELISA in Human.
Background: CEA(Carcinoembryonic antigen) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol(GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells. CEA and related genes make up the CEA family belonging to the immunoglobulin superfamily. In humans, the carcinoembryonic antigen family consists of 29 genes, 18 of which are normally expressed