The Mouse Anti-HDAC2 [3F3] Antibody from MyBioSource.com is a Mouse Monoclonal antibody to HD2, HDAC2, and Histone Deacetylase 2. This antibody recognizes Human, Mouse, Rat, and Bovine antigen. The Mouse Anti-HDAC2 [3F3] Antibody has been shown to work in the following applications: ChIP, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity