Matrix Metalloproteinase 2 (MMP2) from MyBioSource.com

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Matrix Metalloproteinase 2 (MMP2)

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The Matrix Metalloproteinase 2 (MMP2) Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CLG4A, GelA, MMP2, and TBE-1. This antibody recognizes Human antigen. The Matrix Metalloproteinase 2 (MMP2) Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.

Description

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves Collagen Types IV, V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway