The GluN2A/NR2A Antibody: RPE from MyBioSource.com is a Mouse Monoclonal antibody to GluN2A, GRIN2A, NMDAR2A, and NR2A. This antibody recognizes Human, Mouse, and Rat antigen. The GluN2A/NR2A Antibody: RPE has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Background Info: Detects ~170kDa. Does not react with NR2B
Scientific Background: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D)