The HOXA11 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Homeobox A11, HOXA10, and HOXA11. This antibody recognizes Human, Mouse, and Rat antigen. The HOXA11 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia