The KCNH2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to hERG, HERG1, and SQT1. This antibody recognizes Human, Mouse, and Rat antigen. The KCNH2 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1