MyBioSource.com's APOA5 Monoclonal Antibody is a Mouse monoclonal antibody. The APOA5 Monoclonal Antibody was generated using APOA5, and Apolipoprotein A-V as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Immunocytochemistry, and Western Blot.
Description
Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50 -70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum.This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits